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Стоит ли избегать methyl salicylate при беременности? | VeriMom

Harmonised CLP classification lists methyl salicylate as Repr. 2 (H361d), therefore it is scored h=2 (suspected reproductive toxicant). Animal/developmental studies showing reproductive/developmental effects and statements that effects are a function of systemic blood levels support a demonstrated mechanism (m=2). Topical cosmetic use results in low but measurable systemic exposure at typical use levels (SCCS/CIR assessments), so exposure is scored e=1. (Sources: ECHA harmonised classification; SCCS and CIR reviews).

ECHA regulatory hazard statements

  • H361D

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли methyl salicylate при беременности?
Harmonised CLP classification lists methyl salicylate as Repr. 2 (H361d), therefore it is scored h=2 (suspected reproductive toxicant). Animal/developmental studies showing reproductive/developmental effects and statements that effects are a function of systemic blood levels support a demonstrated mechanism (m=2). Topical cosmetic use results in low but measurable systemic exposure at typical use levels (SCCS/CIR assessments), so exposure is scored e=1. (Sources: ECHA harmonised classification; SCCS and CIR reviews).
Безопасен ли methyl salicylate при грудном вскармливании?
Same harmonised reproductive classification applies to lactation concerns (h=2). Mechanistically, systemic absorption and metabolism to salicylate (which can distribute systemically and has been reported in blood) support demonstrated transfer potential (m=2). Dermal cosmetic use gives low but measurable maternal systemic exposure; therefore infant exposure via milk is possible but expected to be low (e=1).
Безопасен ли methyl salicylate для кожи малыша?
SCCS specifically reassessed children 0–3 years and set much lower safe-use limits (e.g., 0.02% in most products for 0–3 y), citing higher risk from systemic exposure in young children. Because harmonised H361d applies, hazard stays h=2. Mechanistic/animal data support demonstrated reproductive/developmental toxicity (m=2). Exposure for baby skin is increased by +1 relative to adults because of immature barrier and higher per‑kg uptake, so e=2 (adult e=1 → infant e=2).
Как VeriMom оценивает methyl salicylate?
VeriMom оценивает methyl salicylate в 20/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
Какие безопасные альтернативы methyl salicylate при беременности?
См. наш список безопасных альтернатив methyl salicylate с аналогичной функцией и классификацией без известных рисков.

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Медицинская оговорка

Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.

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