Стоит ли избегать methyl morpholine oxide при беременности? | VeriMom

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FAQ

Безопасен ли methyl morpholine oxide при беременности?

ECHA lists 4‑methylmorpholine 4‑oxide (N‑methylmorpholine N‑oxide; CAS 7529‑22‑8) with a harmonised CLP reproductive hazard H361f (suspected of damaging fertility), which supports a suspected reproductive hazard (h=2). A specific molecular mechanism for reproductive effects is not described in available dossiers, so mechanism is scored as theoretical/uncertain (m=1). For typical topical cosmetic use dermal exposure is low but measurable (hydrophilic substance, low logP), so adult exposure is scored low (e=1). Sources: ECHA classification and supplier/MSDS listings.

Безопасен ли methyl morpholine oxide при грудном вскармливании?

Harmonised H361f (ECHA) applies to general reproductive/fertility concern and is the principal driver (h=2). No clear data on mammary/milk transfer or neonatal toxicity were found; mechanism remains uncharacterized (m=1). Given the compound's hydrophilicity and expected low dermal/systemic absorption from cosmetics, exposure via topical maternal use is judged low (e=1), but milk transfer data are lacking.

Безопасен ли methyl morpholine oxide для кожи малыша?

Hazard remains driven by harmonised H361f → h=2. Mechanistic evidence is lacking (m=1). Because infant skin (0–3 yr) has higher surface‑area‑to‑weight and an immature barrier, exposure score is increased by +1 compared with adult (adult e=1 → baby e=2) where measurable dermal absorption is plausible. No infant‑specific toxicity or exposure studies were found.

Как VeriMom оценивает methyl morpholine oxide?

VeriMom оценивает methyl morpholine oxide в 27/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы methyl morpholine oxide при беременности?

См. наш список безопасных альтернатив methyl morpholine oxide с аналогичной функцией и классификацией без известных рисков.