Стоит ли избегать methyl estradiolpropanoate при беременности? | VeriMom

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли methyl estradiolpropanoate при беременности?

Topical Methyl Estradiolpropanoate (MEP) has been shown in human studies to activate estrogenic effects in skin (clinical trials of Emepelle products), indicating estrogen receptor activity and potential for systemic exposure; estradiol and active estrogens have known reproductive/teratogenic risks in pregnancy, so this derivative is a suspected reproductive hazard. Sources: clinical studies showing topical efficacy and product ingredient lists. (PubMed clinical trial; product ingredient pages).

Безопасен ли methyl estradiolpropanoate при грудном вскармливании?

Because MEP is an estrogen derivative with demonstrated topical activity, it is reasonably suspected to produce systemic estrogenic exposure after dermal application; estradiol transfers into breast milk, so a conservative classification is 'suspected' hazard for breastfeeding unless data showing negligible systemic absorption are provided. No regulatory harmonised CMR classification or EU ban/restriction was found to override this assessment.

Безопасен ли methyl estradiolpropanoate для кожи малыша?

Hazard and mechanism mirror adults (suspected estrogenic reproductive hazard / demonstrated estrogen receptor activity). Exposure score is increased for infant skin because infant skin has higher absorption (immature barrier, higher surface‑area‑to‑weight) and the ingredient has measurable topical activity in adults, so exposure to a baby (0–3 yr) would be higher.

Как VeriMom оценивает methyl estradiolpropanoate?

VeriMom оценивает methyl estradiolpropanoate в 33/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы methyl estradiolpropanoate при беременности?

См. наш список безопасных альтернатив methyl estradiolpropanoate с аналогичной функцией и классификацией без известных рисков.