VeriMomСтоит ли избегать methoxyethyl acrylate при беременности? | VeriMom
EU harmonised classification (Annex VI/CLP, Delegated Regulation 2020/1182) lists 2‑methoxyethyl acrylate with H360FD (may damage fertility and the unborn child), which by your scoring rules requires h=3. The reproductive hazard is supported by regulatory and literature evidence that glycol‑ether metabolites (e.g. 2‑methoxyethanol) cause reproductive/developmental effects in animal studies and occupational epidemiology, indicating a demonstrated mechanism via toxic metabolites. Dermal and inhalation uptake is documented for glycol ethers and acrylate monomers, so moderate exposure (e=2) is appropriate for topical use unless formulation/impurity data show otherwise.
ECHA regulatory hazard statements
- •H360FD
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли methoxyethyl acrylate при беременности?
- EU harmonised classification (Annex VI/CLP, Delegated Regulation 2020/1182) lists 2‑methoxyethyl acrylate with H360FD (may damage fertility and the unborn child), which by your scoring rules requires h=3. The reproductive hazard is supported by regulatory and literature evidence that glycol‑ether metabolites (e.g. 2‑methoxyethanol) cause reproductive/developmental effects in animal studies and occupational epidemiology, indicating a demonstrated mechanism via toxic metabolites. Dermal and inhalation uptake is documented for glycol ethers and acrylate monomers, so moderate exposure (e=2) is appropriate for topical use unless formulation/impurity data show otherwise.
- Безопасен ли methoxyethyl acrylate при грудном вскармливании?
- Harmonised CLP classification H360FD applies irrespective of route and signals potential for effects to reproduction and the developing offspring; metabolic conversion to 2‑methoxyethanol supports a demonstrated mechanism (m=2). Dermal absorption and systemic availability have been reported for glycol ethers/monomeric acrylates, so maternal topical exposure could result in systemic exposure (e=2); transfer in breastmilk is plausible for small polar metabolites though breastmilk‑specific data are lacking.
- Безопасен ли methoxyethyl acrylate для кожи малыша?
- Hazard remains high (h=3) because of the harmonised H360FD classification. Mechanistic concern is the same (metabolic formation of 2‑methoxyethanol). Exposure score is increased by +1 for infants (per your rules) because baby skin has higher absorption and the parent compound/ metabolites are systemically available; therefore exposure is high (e=3) for 0–3 yr when present on skin in monomeric form.
- Как VeriMom оценивает methoxyethyl acrylate?
- VeriMom оценивает methoxyethyl acrylate в 13/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы methoxyethyl acrylate при беременности?
- См. наш список безопасных альтернатив methoxyethyl acrylate с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.