Стоит ли избегать m-phenylenediamine при беременности? | VeriMom

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли m-phenylenediamine при беременности?

CIR’s safety review (1997 summary) reports one animal study with fetal deaths (other studies negative) and identifies measurable percutaneous absorption and metabolites — this supports a “suspected” reproductive hazard (h=2) rather than confirmed teratogen. No well‑characterised reproductive mechanism was found, only limited mechanistic data (hence m=1). Dermal absorption from hair‑dye use is reported as low but measurable, so exposure from typical topical cosmetic use is scored e=1. (Sources: CIR summary/CosmeticsInfo; PubMed animal study; ECHA registration dossier.)

Безопасен ли m-phenylenediamine при грудном вскармливании?

There are no robust human breastfeeding studies identified. The same animal evidence (fetal death in at least one study) and CIR finding of measurable dermal absorption support a conservative ‘suspected’ hazard for reproductive/developmental endpoints (h=2) and a theoretical mechanism only (m=1). Dermal exposure during use (hair dyes) is low but measurable (e=1); transfer into breastmilk was not specifically documented in available sources. (Sources: CIR summary/CosmeticsInfo; PubMed study; ECHA dossier.)

Безопасен ли m-phenylenediamine для кожи малыша?

Hazard (h) and mechanism (m) are unchanged because no infant‑specific reproductive mechanism data were found. Adult dermal absorption is measurable; per instructions, increase exposure score by +1 for 0–3‑year‑old skin when absorption is measurable — adult e=1 → baby e=2. No infant‑specific dermal absorption or toxicokinetic studies were located. (Sources: CIR summary/CosmeticsInfo; ECHA registration; guidance on absorption in CIR review.)

Как VeriMom оценивает m-phenylenediamine?

VeriMom оценивает m-phenylenediamine в 27/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы m-phenylenediamine при беременности?

См. наш список безопасных альтернатив m-phenylenediamine с аналогичной функцией и классификацией без известных рисков.