Стоит ли избегать lead acetate при беременности? | VeriMom
Lead di(acetate) (CAS 301-04-2) is listed in EU regulatory sources with a harmonised classification for reproductive toxicity (H360 — may damage fertility or the unborn child), which per your scoring rules mandates h=3. Maternal–fetal transfer of lead and fetal exposure are documented (demonstrated placental transfer and mobilization of maternal bone lead during pregnancy), supporting m=2. Absorption from topical cosmetic use is generally low but not zero (historical use as a scalp hair colorant and regulatory attention indicate measurable exposure potential), so exposure for topical cosmetic uses is scored as 1 (low but measurable).
ECHA regulatory hazard statements
- •H360DF
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли lead acetate при беременности?
- Lead di(acetate) (CAS 301-04-2) is listed in EU regulatory sources with a harmonised classification for reproductive toxicity (H360 — may damage fertility or the unborn child), which per your scoring rules mandates h=3. Maternal–fetal transfer of lead and fetal exposure are documented (demonstrated placental transfer and mobilization of maternal bone lead during pregnancy), supporting m=2. Absorption from topical cosmetic use is generally low but not zero (historical use as a scalp hair colorant and regulatory attention indicate measurable exposure potential), so exposure for topical cosmetic uses is scored as 1 (low but measurable).
- Безопасен ли lead acetate при грудном вскармливании?
- Because the substance carries a harmonised H360 classification (reproductive hazard) it is scored h=3 for lactation/breastfeeding contexts. Lead is known to be present in maternal blood and to partition into breast milk with documented correlations between maternal blood lead and infant exposure, supporting m=2. For cosmetic topical use the expected maternal systemic uptake is low but measurable so e=1 (low but measurable) for breastfeeding exposure from maternal cosmetic use.
- Безопасен ли lead acetate для кожи малыша?
- Hazard remains high (h=3) driven by the harmonised H360 reproductive classification for this lead compound. Mechanistic evidence for maternal–fetal transfer and established systemic toxicity of lead justify m=2. Per your rules, if adult exposure is measurable (e=1), increase baby skin exposure by +1; therefore infant (0–3 y) topical exposure is e=2 (moderate), since infant skin has higher absorption and surface-area-to-weight ratio and lead is a bioavailable metal capable of systemic uptake.
- Как VeriMom оценивает lead acetate?
- VeriMom оценивает lead acetate в 20/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы lead acetate при беременности?
- См. наш список безопасных альтернатив lead acetate с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.