Стоит ли избегать isopropylparaben при беременности? | VeriMom

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли isopropylparaben при беременности?

Isopropylparaben (isopropyl 4‑hydroxybenzoate, CAS 4191‑73‑5) is restricted/prohibited in the EU for cosmetics (Annex II of Regulation 1223/2009), reflecting regulatory concern about certain higher alkyl parabens and reproductive/ endocrine effects. There are in vitro reports of estrogenic activity for some parabens (isopropylparaben reported as relatively active in some screens) and animal toxicity dossiers on ECHA; taken together this supports a 'suspected' reproductive/ developmental concern (h=2) and a demonstrated in vitro endocrine mechanism (m=2). Topical cosmetic use gives low but measurable systemic exposure (e=1). Sources: EU Annex II (cosmetics), ECHA registration dossier, peer‑reviewed and review sources listed below.

Безопасен ли isopropylparaben при грудном вскармливании?

Same hazard and mechanism considerations as pregnancy (suspected reproductive/endocrine activity). There are no robust human lactation studies showing clear transfer or infant effects; however parabens can be systemically absorbed after topical use at low levels, so breastfeeding exposure is considered low but measurable (e=1). Regulatory prohibition in cosmetics supports caution for lactating people.

Безопасен ли isopropylparaben для кожи малыша?

Hazard and mechanism scores follow adult reproductive assessment (suspected endocrine/reproductive concern; in vitro activity). Exposure (e) is increased by +1 for infants (0–3 yr) because immature barrier and higher surface‑area‑to‑weight make percutaneous absorption and systemic dose relatively higher; thus e=2. Note: there are few infant‑specific toxicology studies for isopropylparaben, but regulatory bans on this paraben class in the EU for leave‑on/rinse‑off cosmetic uses indicate a conservative approach for infant products.

Как VeriMom оценивает isopropylparaben?

VeriMom оценивает isopropylparaben в 20/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы isopropylparaben при беременности?

См. наш список безопасных альтернатив isopropylparaben с аналогичной функцией и классификацией без известных рисков.