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HIGH RISK

Стоит ли избегать isolongifolanone при беременности? | VeriMom

Multiple ECHA registration dossiers and downstream Safety Data Sheets report classification as Repr. Cat.2 / H361 (suspected of damaging fertility or the unborn child) (these are notifier/self-classifications in ECHA dossiers and SDSs). I found no harmonised CLP (Annex VI) entry, no SCCS or CIR cosmetic safety opinion, and no peer‑reviewed reproductive‑mechanism data; therefore hazard is scored as 2 based on the H361 classification in registrant documents, mechanism 0 (no demonstrated reproductive mechanism found), and exposure 1 (topical cosmetic use would give low but measurable dermal absorption). Sources: ECHA substance/registration pages and SDSs.

ECHA regulatory hazard statements

  • H361

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли isolongifolanone при беременности?
Multiple ECHA registration dossiers and downstream Safety Data Sheets report classification as Repr. Cat.2 / H361 (suspected of damaging fertility or the unborn child) (these are notifier/self-classifications in ECHA dossiers and SDSs). I found no harmonised CLP (Annex VI) entry, no SCCS or CIR cosmetic safety opinion, and no peer‑reviewed reproductive‑mechanism data; therefore hazard is scored as 2 based on the H361 classification in registrant documents, mechanism 0 (no demonstrated reproductive mechanism found), and exposure 1 (topical cosmetic use would give low but measurable dermal absorption). Sources: ECHA substance/registration pages and SDSs.
Безопасен ли isolongifolanone при грудном вскармливании?
Same hazard basis as pregnancy (H361 reported in ECHA registration dossiers/SDSs → h=2). No publications showing placental/milk transfer or breastfeeding-specific studies were found (m=0). For breastfeeding exposure, dermal absorption from cosmetics is expected to be low but measurable, so e=1 (milk transfer not demonstrated).
Безопасен ли isolongifolanone для кожи малыша?
Hazard retained at h=2 because the reproductive classification (H361) indicates developmental concern in registrant data (no infant‑specific toxicology found). Mechanism not demonstrated in the literature (m=0). Exposure increased by +1 for baby skin (adult e=1 → infant e=2) because infant skin has higher absorption and immature barrier when an ingredient shows measurable dermal absorption.
Как VeriMom оценивает isolongifolanone?
VeriMom оценивает isolongifolanone в 33/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
Какие безопасные альтернативы isolongifolanone при беременности?
См. наш список безопасных альтернатив isolongifolanone с аналогичной функцией и классификацией без известных рисков.

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Медицинская оговорка

Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.

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