Стоит ли избегать hydroxyanasatil retinoate при беременности? | VeriMom

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Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли hydroxyanasatil retinoate при беременности?

No harmonised Annex VI CLP classification was found for CAS 127471-94-7, but the substance is a retinoic acid ester (structural class known to interact with retinoid receptors). Retinoids/retinoic acid are well‑characterised developmental toxicants via RAR/RXR-mediated mechanisms (SCCS and regulatory literature treat vitamin A / some retinoids as reproductive/developmental hazards). Because there is no harmonised H360 entry for this specific CAS and no published specific reproductive animal/human data located for 127471-94-7, hazard is scored as structural/class-based concern only (h=1) while mechanism is rated high (RAR agonism well characterized). Topical absorption from cosmetics is likely low but measurable, so exposure is scored as 1. (Sources: SCCS Vitamin A opinion; supplier/patent records identifying this compound as a retinoate.).

Безопасен ли hydroxyanasatil retinoate при грудном вскармливании?

Same structural/class‑based concern applies for breastfeeding: no specific reproductive/lactation studies found for this CAS, but retinoids have a known RAR/RXR mechanism. Systemic exposure after topical use is expected to be low but potentially measurable; transfer into breast milk has not been reported for this specific substance. Therefore hazard = 1 (structural/class alert), mechanism = 3, exposure = 1 (low but measurable).

Безопасен ли hydroxyanasatil retinoate для кожи малыша?

Infant skin (0–3 yr) has higher surface‑area‑to‑weight and an immature barrier; for a retinoate with measurable absorption in adults we increase exposure by +1 for babies. There are no infant‑specific toxicity or dermal developmental studies for this CAS, so hazard remains a structural/class alert (h=1) and mechanism remains retinoid receptor activity (m=3). Exposure is scored moderate (e=2) for baby skin due to increased per‑kg uptake from topical application.

Как VeriMom оценивает hydroxyanasatil retinoate?

VeriMom оценивает hydroxyanasatil retinoate в 33/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы hydroxyanasatil retinoate при беременности?

См. наш список безопасных альтернатив hydroxyanasatil retinoate с аналогичной функцией и классификацией без известных рисков.