Стоит ли избегать hydrochlorofluorocarbon 22 при беременности? | VeriMom
Chlorodifluoromethane (HCFC-22, CAS 75-45-6) has animal evidence of reproductive/developmental effects (e.g., inhalation studies reporting developmental/teratogenic findings), and ECHA records indicate classification notifications for reproductive toxicity (H361 category). There is no harmonised H360 (known human teratogen) classification in Annex VI, so the weight is 'suspected' not 'confirmed'. Topical cosmetic exposure is effectively negligible for this volatile refrigerant gas (not formulated as a skin ingredient), so exposure from cosmetic use is expected to be negligible. Sources: ECHA substance/C&L data and peer-reviewed animal studies. (ECHA; PubMed).
ECHA regulatory hazard statements
- •H360
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли hydrochlorofluorocarbon 22 при беременности?
- Chlorodifluoromethane (HCFC-22, CAS 75-45-6) has animal evidence of reproductive/developmental effects (e.g., inhalation studies reporting developmental/teratogenic findings), and ECHA records indicate classification notifications for reproductive toxicity (H361 category). There is no harmonised H360 (known human teratogen) classification in Annex VI, so the weight is 'suspected' not 'confirmed'. Topical cosmetic exposure is effectively negligible for this volatile refrigerant gas (not formulated as a skin ingredient), so exposure from cosmetic use is expected to be negligible. Sources: ECHA substance/C&L data and peer-reviewed animal studies. (ECHA; PubMed).
- Безопасен ли hydrochlorofluorocarbon 22 при грудном вскармливании?
- Same basis as pregnancy: animal reproductive/developmental toxicity evidence supports 'suspected' risk (H361-level). No reliable human breastfeeding transfer data specific to cosmetic topical use; cosmetic topical exposure would be negligible. Mechanistic data are limited (no well-characterised reproductive mechanism demonstrated), so mechanism scored as theoretical/limited.
- Безопасен ли hydrochlorofluorocarbon 22 для кожи малыша?
- Hazard (h=2) follows the same animal evidence / ECHA reproductive suspicion. For exposure, topical cosmetic use in practice is unlikely (adult e=0), but because infants (0–3 y) have a higher surface-area-to-weight ratio and immature barrier, exposure score is increased by +1 to e=1 per your rules if any measurable absorption is plausible. There are no infant-specific absorption or toxicity studies for topical application.
- Как VeriMom оценивает hydrochlorofluorocarbon 22?
- VeriMom оценивает hydrochlorofluorocarbon 22 в 33/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы hydrochlorofluorocarbon 22 при беременности?
- См. наш список безопасных альтернатив hydrochlorofluorocarbon 22 с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.