VeriMomСтоит ли избегать ethylhexanol при беременности? | VeriMom
Animal developmental/toxicity studies in rodents (dermal and dietary studies) do not show teratogenicity or consistent developmental toxicity at doses up to high levels; authoritative registries (ECHA registration / PubChem summary of NTP studies) report no developmental or maternal effects at tested doses. No harmonised CLP H360 classification was found; some safety data sheets/C&L notifications list suspected reproductive hazard (H361) but these appear to be company notifications rather than an EU-harmonised classification, so they do not by themselves justify raising the hazard score. Topical cosmetic exposure would be expected to give low but measurable systemic exposure. (Tyl et al. 1992; PubChem/NTP summary; ECHA substance/registration information).
ECHA regulatory hazard statements
- •H361
- •H361D
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Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли ethylhexanol при беременности?
- Animal developmental/toxicity studies in rodents (dermal and dietary studies) do not show teratogenicity or consistent developmental toxicity at doses up to high levels; authoritative registries (ECHA registration / PubChem summary of NTP studies) report no developmental or maternal effects at tested doses. No harmonised CLP H360 classification was found; some safety data sheets/C&L notifications list suspected reproductive hazard (H361) but these appear to be company notifications rather than an EU-harmonised classification, so they do not by themselves justify raising the hazard score. Topical cosmetic exposure would be expected to give low but measurable systemic exposure. (Tyl et al. 1992; PubChem/NTP summary; ECHA substance/registration information).
- Безопасен ли ethylhexanol при грудном вскармливании?
- No reliable mammalian data show reproductive/developmental effects at relevant exposures and no authoritative guidance (CIR or SCCS) listing as unsafe in lactation was located. Systemic absorption from topical use is expected to be low but measurable, so small amounts could theoretically reach breast milk, but direct data on milk transfer are lacking. Company SDS/C&L notifications claiming H361 are not harmonised and do not provide definitive evidence of lactation risk. (PubChem/NTP; ECHA registration/dossier).
- Безопасен ли ethylhexanol для кожи малыша?
- No infant-specific developmental or reproductive toxicity data were identified. Given measurable dermal absorption in adults and the increased surface-area-to-weight and immature barrier in infants, exposure rating is increased by one for baby skin (adult e=1 → baby e=2). The available rodent developmental studies do not indicate teratogenicity at tested doses. Recent non-mammalian studies (zebrafish) report neurodevelopmental effects, but these are not directly translatable to human infant skin/ systemic risk without further mammalian evidence. (Tyl et al. 1992; recent zebrafish study; PubChem/ECHA summaries).
- Как VeriMom оценивает ethylhexanol?
- VeriMom оценивает ethylhexanol в 33/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы ethylhexanol при беременности?
- См. наш список безопасных альтернатив ethylhexanol с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.