Стоит ли избегать ethylenediamine при беременности? | VeriMom
Ethylenediamine (CAS 107-15-3) is listed in recent ECHA documents as having a reproductive hazard classification (H361 — 'suspected of damaging fertility or the unborn child'), which justifies a 'suspected' reproductive hazard score (h=2). No clear, specific mechanistic data (e.g., endocrine receptor activity or well-characterized reproductive mechanism) were found to support raising the mechanism score, so m=0. For topical cosmetic use, systemic absorption would likely be low but measurable for a small, water‑soluble amine, so exposure is scored as low/measurable (e=1). Sources: ECHA Member State/CLP documentation and registration pages; supplier SDSs noting H361. ([chesar.echa.europa.eu](https://chesar.echa.europa.eu/documents/10162/c017865b-6d6d-d041-4d6a-f71700166a6b?utm_source=openai))
ECHA regulatory hazard statements
- •H226
- •H312
- •H302
- •H314
- •H334
- •H317
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли ethylenediamine при беременности?
- Ethylenediamine (CAS 107-15-3) is listed in recent ECHA documents as having a reproductive hazard classification (H361 — 'suspected of damaging fertility or the unborn child'), which justifies a 'suspected' reproductive hazard score (h=2). No clear, specific mechanistic data (e.g., endocrine receptor activity or well-characterized reproductive mechanism) were found to support raising the mechanism score, so m=0. For topical cosmetic use, systemic absorption would likely be low but measurable for a small, water‑soluble amine, so exposure is scored as low/measurable (e=1). Sources: ECHA Member State/CLP documentation and registration pages; supplier SDSs noting H361. ([chesar.echa.europa.eu](https://chesar.echa.europa.eu/documents/10162/c017865b-6d6d-d041-4d6a-f71700166a6b?utm_source=openai))
- Безопасен ли ethylenediamine при грудном вскармливании?
- Hazard is scored the same as pregnancy (h=2) because the harmonised/suspected reproductive classification applies to fertility/developmental concerns and no infant‑specific data alter hazard. No mechanistic data showing transfer into milk or a specific lactation hazard were identified (m=0). For maternal topical cosmetic use, systemic exposure would generally be low but could be measurable (e=1); without data on milk transfer, exposure is conservatively scored as low/measurable. Key sources include ECHA documentation and toxicity dossiers; no breastmilk or lactation studies were located. ([chesar.echa.europa.eu](https://chesar.echa.europa.eu/documents/10162/c017865b-6d6d-d041-4d6a-f71700166a6b?utm_source=openai))
- Безопасен ли ethylenediamine для кожи малыша?
- Hazard remains 'suspected' (h=2) based on the ECHA reproductive classification. Mechanistic evidence specific to infants (m) was not found. Exposure for baby skin is increased by +1 relative to adults because infant skin barrier immaturity and higher surface‑area‑to‑weight ratio make percutaneous exposure more likely; given adult topical exposure is low/measurable (e=1), baby skin exposure is scored e=2. No infant dermal absorption studies specific to ethylenediamine were found. ([chesar.echa.europa.eu](https://chesar.echa.europa.eu/documents/10162/c017865b-6d6d-d041-4d6a-f71700166a6b?utm_source=openai))
- Как VeriMom оценивает ethylenediamine?
- VeriMom оценивает ethylenediamine в 33/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы ethylenediamine при беременности?
- См. наш список безопасных альтернатив ethylenediamine с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.