VeriMomСтоит ли избегать ethyl dimethyl paba при беременности? | VeriMom
Multiple regulatory/supplier sources (ECHA registration page and several up‑to‑date SDS/product pages) report Ethyl 4-(dimethylamino)benzoate (CAS 10287-53-3, a.k.a. Ethyl Dimethyl PABA / EDAB) with Repr.1B / H360 classification or list reproductive/developmental toxicity in dossiers, which corresponds to a harmonised‑level reproductive hazard (H360 → h=3). Mechanistic evidence is limited but ECHA/registration notes and repeated test summaries indicate developmental/reproductive effects in animal test data (supporting m=2). For topical cosmetic use absorption is plausible for a small lipophilic ester (not an inert mineral) so exposure is assessed as moderate (e=2). Sources: ECHA registration/brief profile and supplier SDS/product pages listed below.
ECHA regulatory hazard statements
- •H360
- •H360F
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли ethyl dimethyl paba при беременности?
- Multiple regulatory/supplier sources (ECHA registration page and several up‑to‑date SDS/product pages) report Ethyl 4-(dimethylamino)benzoate (CAS 10287-53-3, a.k.a. Ethyl Dimethyl PABA / EDAB) with Repr.1B / H360 classification or list reproductive/developmental toxicity in dossiers, which corresponds to a harmonised‑level reproductive hazard (H360 → h=3). Mechanistic evidence is limited but ECHA/registration notes and repeated test summaries indicate developmental/reproductive effects in animal test data (supporting m=2). For topical cosmetic use absorption is plausible for a small lipophilic ester (not an inert mineral) so exposure is assessed as moderate (e=2). Sources: ECHA registration/brief profile and supplier SDS/product pages listed below.
- Безопасен ли ethyl dimethyl paba при грудном вскармливании?
- Same hazard basis applies to breastfeeding exposure because the substance is classified as a presumed reproductive toxicant (H360/Repr.1B) in regulatory/product sources; mechanisms show animal developmental/reproductive effects (m=2). Dermal/topical exposure would give measurable systemic uptake (e=2), so potential transfer into milk cannot be excluded.
- Безопасен ли ethyl dimethyl paba для кожи малыша?
- Hazard and mechanism scores follow the parental classification (H360/Repr.1B → h=3; mechanistic evidence m=2). Exposure for infant skin is increased relative to adults (add +1 to adult exposure) because the ingredient is small/lipophilic with measurable dermal absorption — adult e=2 → baby e=3. There are no infant‑specific safety studies located that would reduce concern; therefore conservative infant exposure scoring applied.
- Как VeriMom оценивает ethyl dimethyl paba?
- VeriMom оценивает ethyl dimethyl paba в 13/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы ethyl dimethyl paba при беременности?
- См. наш список безопасных альтернатив ethyl dimethyl paba с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.