Стоит ли избегать ethinylestradiol при беременности? | VeriMom

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли ethinylestradiol при беременности?

Ethinylestradiol (CAS 57-63-6) has a harmonised CLP classification as Repr. 1B (H360—may damage fertility or the unborn child) per ECHA, which meets the criterion for h=3. It is a potent synthetic estrogen with demonstrated estrogen receptor agonism and animal data showing adverse effects on fetal growth/survival, supporting m=2. For topical cosmetic use, systemic exposure from a cosmetic formulation would be negligible/very low, so e=0 (noting ethinylestradiol is primarily used as an oral/vaginal pharmaceutical rather than a cosmetic). ([echa.europa.eu](https://echa.europa.eu/brief-profile/-/briefprofile/100.014.129?utm_source=openai))

Безопасен ли ethinylestradiol при грудном вскармливании?

Harmonised classification H360 (Repr. 1B) equally flags lactation-related reproductive hazard (h=3). Mechanistically, ethinylestradiol is an estrogen receptor agonist with demonstrated endocrine activity (m=2). Human studies indicate transfer into breast milk is negligible with low‑dose combined hormonal contraceptives, so exposure via milk from typical systemic use is low but measurable (e=1); for topical cosmetic use systemic uptake would be expected to be very low. ([echa.europa.eu](https://echa.europa.eu/brief-profile/-/briefprofile/100.014.129?utm_source=openai))

Безопасен ли ethinylestradiol для кожи малыша?

Hazard (H360 Repr. 1B) remains (h=3). Mechanistic evidence of estrogenic activity supports m=2. For topical cosmetic use adult dermal exposure is expected to be negligible (adult e=0); per the scoring rules, baby skin exposure is increased by +1 (e=1) because infant skin is more permeable — although ethinylestradiol is not a typical cosmetic ingredient and meaningful topical cosmetic exposure is unlikely. Animal studies show prenatal/placental effects but no infant‑specific dermal data were found. ([echa.europa.eu](https://echa.europa.eu/brief-profile/-/briefprofile/100.014.129?utm_source=openai))

Как VeriMom оценивает ethinylestradiol?

VeriMom оценивает ethinylestradiol в 27/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы ethinylestradiol при беременности?

См. наш список безопасных альтернатив ethinylestradiol с аналогичной функцией и классификацией без известных рисков.