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Стоит ли избегать dipropylene glycol salicylate при беременности? | VeriMom

No evidence of a harmonised CLP H360 or an EU Annex II/III restriction for dipropylene glycol salicylate was found (no EU ban/restriction). Several safety sources treat it as an ester of salicylic acid; the CIR assessment of salicylic acid/salicylates and government reviews report reproductive/developmental effects only at relatively high systemic doses in animals, not from topical cosmetic use. Some SDSs list H361 but these appear to be company self-classifications rather than a harmonised ECHA classification. Given the structural link to salicylic acid (structural/class-based concern) but absence of harmonised classification or robust reproductive studies on this exact compound, I assign a conservative h=1 (structural/class concern), m=1 (theoretical/mechanistic plausibility via ester → salicylate), e=1 (low but measurable dermal exposure for typical cosmetic use). Sources: PubChem, CIR salicylates review, Canada draft screening (salicylates), EWG, manufacturer/SDS notes.

ECHA regulatory hazard statements

  • H361

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли dipropylene glycol salicylate при беременности?
No evidence of a harmonised CLP H360 or an EU Annex II/III restriction for dipropylene glycol salicylate was found (no EU ban/restriction). Several safety sources treat it as an ester of salicylic acid; the CIR assessment of salicylic acid/salicylates and government reviews report reproductive/developmental effects only at relatively high systemic doses in animals, not from topical cosmetic use. Some SDSs list H361 but these appear to be company self-classifications rather than a harmonised ECHA classification. Given the structural link to salicylic acid (structural/class-based concern) but absence of harmonised classification or robust reproductive studies on this exact compound, I assign a conservative h=1 (structural/class concern), m=1 (theoretical/mechanistic plausibility via ester → salicylate), e=1 (low but measurable dermal exposure for typical cosmetic use). Sources: PubChem, CIR salicylates review, Canada draft screening (salicylates), EWG, manufacturer/SDS notes.
Безопасен ли dipropylene glycol salicylate при грудном вскармливании?
Same rationale as pregnancy: no direct harmonised reproductive classification or authoritative restriction for this specific ester, but it is an ester of salicylic acid which can be systemically active after absorption/hydrolysis. Dermal cosmetic use is expected to give low but measurable maternal systemic exposure in normal use; transfer into breastmilk would be contingent on maternal systemic levels. Conservative approach: same scores as pregnancy.
Безопасен ли dipropylene glycol salicylate для кожи малыша?
Hazard (h) and mechanism (m) unchanged — no infant-specific reproductive/developmental data; however exposure (e) increased by +1 because infant skin (0–3 y) has higher surface-area-to-body-weight and an immature barrier, so measured dermal absorption for the parent compound would translate to higher internal exposure in infants. There is no evidence that infant topical use has produced harm for this specific ingredient, but prudence supports increased exposure score for baby skin.
Как VeriMom оценивает dipropylene glycol salicylate?
VeriMom оценивает dipropylene glycol salicylate в 27/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
Какие безопасные альтернативы dipropylene glycol salicylate при беременности?
См. наш список безопасных альтернатив dipropylene glycol salicylate с аналогичной функцией и классификацией без известных рисков.

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Медицинская оговорка

Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.

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