Стоит ли избегать dinonyl phenol при беременности? | VeriMom
Dinonyl phenol (CAS 1323-65-5) appears on registries and supplier/MSDSs that carry the hazard statement H361 ("suspected of damaging fertility or the unborn child") in product classifications (company/SDS level), and it is a high-logP alkylphenol (lipophilic) which places it in a chemical class with known endocrine/estrogenic concerns (alkylphenols). Because a harmonised (Annex VI) CLP classification from ECHA or an SCCS/CIR cosmetic safety opinion specific to dinonyl phenol was not found, the conservative score follows the presence of H361 (suspected) rather than H360 (confirmed). Sources: ECHA registration/brief/profile pages and multiple SDS entries showing H361; PubChem brief substance entry.
ECHA regulatory hazard statements
- •H361
- •H361FD
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли dinonyl phenol при беременности?
- Dinonyl phenol (CAS 1323-65-5) appears on registries and supplier/MSDSs that carry the hazard statement H361 ("suspected of damaging fertility or the unborn child") in product classifications (company/SDS level), and it is a high-logP alkylphenol (lipophilic) which places it in a chemical class with known endocrine/estrogenic concerns (alkylphenols). Because a harmonised (Annex VI) CLP classification from ECHA or an SCCS/CIR cosmetic safety opinion specific to dinonyl phenol was not found, the conservative score follows the presence of H361 (suspected) rather than H360 (confirmed). Sources: ECHA registration/brief/profile pages and multiple SDS entries showing H361; PubChem brief substance entry.
- Безопасен ли dinonyl phenol при грудном вскармливании?
- Given the substance' high lipophilicity (very large estimated logP) and supplier/SDS classifications indicating reproductive hazard (H361), there is a plausible route for systemic uptake and accumulation and therefore transfer into breastmilk is a reasonable concern. No high-quality human milk monitoring or lactation-specific studies for dinonyl phenol were located, so the hazard rating follows the H361 evidence and mechanistic concern is class-based (alkylphenol estrogenicity).
- Безопасен ли dinonyl phenol для кожи малыша?
- For infant (0–3 yr) skin the hazard remains the same (H361-level evidence -> suspected reproductive/ developmental hazard). Exposure (e) is increased by +1 relative to adults because infant skin has higher surface-area-to-body-weight and an immature barrier, and dinonyl phenol is lipophilic with supplier/SDS notes that it can be absorbed through skin. No infant-specific dermal absorption or toxicity studies were found to change hazard or mechanism scores.
- Как VeriMom оценивает dinonyl phenol?
- VeriMom оценивает dinonyl phenol в 27/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы dinonyl phenol при беременности?
- См. наш список безопасных альтернатив dinonyl phenol с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.