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Стоит ли избегать dimethyl lauramine при беременности? | VeriMom

EU Cosmetic Regulation (COSING / Annex III) restricts dimethyl lauramine (N,N‑dimethyldodecylamine, CAS 112‑18‑5) in cosmetic products (maximum 2.5% in leave‑on products and strict purity/secondary‑amine/nitrosamine limits), which creates a regulatory reproductive/contamination concern (nitrosation risk). No clear harmonised CLH (Annex VI) Category 1 CMR (H360/H350/H340) was found; no robust reproductive/developmental animal studies locating direct teratogenicity or fertility effects were located in PubMed or primary dossiers. Therefore hazard is scored as a regulatory/class‑based concern (h=1). Sources: COSING / Annex III restriction, ECHA substance pages, OECD SIDS, PubChem.

ECHA regulatory hazard statements

  • H361

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли dimethyl lauramine при беременности?
EU Cosmetic Regulation (COSING / Annex III) restricts dimethyl lauramine (N,N‑dimethyldodecylamine, CAS 112‑18‑5) in cosmetic products (maximum 2.5% in leave‑on products and strict purity/secondary‑amine/nitrosamine limits), which creates a regulatory reproductive/contamination concern (nitrosation risk). No clear harmonised CLH (Annex VI) Category 1 CMR (H360/H350/H340) was found; no robust reproductive/developmental animal studies locating direct teratogenicity or fertility effects were located in PubMed or primary dossiers. Therefore hazard is scored as a regulatory/class‑based concern (h=1). Sources: COSING / Annex III restriction, ECHA substance pages, OECD SIDS, PubChem.
Безопасен ли dimethyl lauramine при грудном вскармливании?
Same basis as pregnancy: regulatory restriction (Annex III) and nitrosamine/impurity concerns drive conservative flagging. No data located showing transfer into breastmilk or specific lactation/developmental toxicity; mechanism concern is theoretical (nitrosamine formation from amine impurities). Exposure from topical cosmetic use is low but measurable. Sources: COSING (Annex III restriction), ECHA/CHEM listings, PubChem.
Безопасен ли dimethyl lauramine для кожи малыша?
Hazard and mechanism same as for adults (regulatory restriction due to nitrosation risk and impurity control) so h and m remain 1. Exposure is increased for infants because skin barrier immaturity and higher surface‑area‑to‑weight markedly increase potential systemic uptake for substances with measurable dermal absorption (here estimated as low→adult e=1, increased by +1 for infant skin → e=2). No infant‑specific reproductive or developmental toxicity studies were found. Sources: EU Annex III/COSING restrictions and ingredient listings (supporting exposure/purity limits) and ECHA registration/dossier listings.
Как VeriMom оценивает dimethyl lauramine?
VeriMom оценивает dimethyl lauramine в 27/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
Какие безопасные альтернативы dimethyl lauramine при беременности?
См. наш список безопасных альтернатив dimethyl lauramine с аналогичной функцией и классификацией без известных рисков.

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Медицинская оговорка

Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.

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