VeriMomСтоит ли избегать dimethyl imidazolidinone при беременности? | VeriMom
Multiple supplier SDS and registration records list 1,3‑dimethyl‑2‑imidazolidinone (CAS 80‑73‑9, also called dimethylimidazolidinone, DMI) as Reproductive Toxicity Category 2 (H361, “suspected of damaging fertility or the unborn child”), and ECHA’s Registry of CLH intentions shows a CLH proposal has been submitted for this substance. These items support a suspected reproductive hazard (H361 → h=2) though a legally binding harmonised CLH entry does not appear to be published as an adopted harmonised classification yet; mechanistic data are limited, so mechanism is scored as theoretical only. DMI is a low‑molecular‑weight polar solvent with measurable dermal absorption in typical solvent roles, so topical cosmetic exposure is assessed as moderate. (Sources: ECHA substance page; ECHA Registry of CLH intentions; supplier SDS/C&L notifications; EWG summary).
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли dimethyl imidazolidinone при беременности?
- Multiple supplier SDS and registration records list 1,3‑dimethyl‑2‑imidazolidinone (CAS 80‑73‑9, also called dimethylimidazolidinone, DMI) as Reproductive Toxicity Category 2 (H361, “suspected of damaging fertility or the unborn child”), and ECHA’s Registry of CLH intentions shows a CLH proposal has been submitted for this substance. These items support a suspected reproductive hazard (H361 → h=2) though a legally binding harmonised CLH entry does not appear to be published as an adopted harmonised classification yet; mechanistic data are limited, so mechanism is scored as theoretical only. DMI is a low‑molecular‑weight polar solvent with measurable dermal absorption in typical solvent roles, so topical cosmetic exposure is assessed as moderate. (Sources: ECHA substance page; ECHA Registry of CLH intentions; supplier SDS/C&L notifications; EWG summary).
- Безопасен ли dimethyl imidazolidinone при грудном вскармливании?
- Same hazard basis as pregnancy (listed as Repr. Cat.2 / H361 in registration/SDS material and under active CLH proposal). Mechanism evidence is limited. Dermal/topical exposure could lead to systemic exposure (moderate expected dermal absorption), so breastfeeding exposure is scored as moderate (e=2) because systemic maternal exposure could lead to transfer into milk if maternal systemic levels occur.
- Безопасен ли dimethyl imidazolidinone для кожи малыша?
- Hazard and mechanism scores follow the same evidence (H361 / Repr. Cat.2 reporting and CLH proposal). Because DMI has measurable dermal absorption as a small polar solvent, infant skin (0–3 yr) receives a higher exposure score (+1 per guidance) relative to adults, so exposure is scored high. There is no specific infant toxicity data found to alter hazard or mechanism scores.
- Как VeriMom оценивает dimethyl imidazolidinone?
- VeriMom оценивает dimethyl imidazolidinone в 20/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы dimethyl imidazolidinone при беременности?
- См. наш список безопасных альтернатив dimethyl imidazolidinone с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.