Стоит ли избегать diethylene glycol/propylene glycol/dipropylene glycol dibenzoate при беременности? | VeriMom
ECHA registration/substance entries and C&L information for the reaction mass of diethylene glycol dibenzoate and dipropylene glycol dibenzoate list reproductive toxicity category Repr.2 (H361) in classification/notifications, so this meets the criteria for h=2 (suspected reproductive hazard). There is no high-confidence mechanistic reproductive mode reported in the literature (mechanistic evidence is limited), so mechanism is scored as 1. Dermal cosmetic use of relatively large, lipophilic dibenzoate esters suggests low but measurable systemic absorption (e=1). (Sources: ECHA registration/substance pages; PubChem and manufacturer safety assessments.)
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли diethylene glycol/propylene glycol/dipropylene glycol dibenzoate при беременности?
- ECHA registration/substance entries and C&L information for the reaction mass of diethylene glycol dibenzoate and dipropylene glycol dibenzoate list reproductive toxicity category Repr.2 (H361) in classification/notifications, so this meets the criteria for h=2 (suspected reproductive hazard). There is no high-confidence mechanistic reproductive mode reported in the literature (mechanistic evidence is limited), so mechanism is scored as 1. Dermal cosmetic use of relatively large, lipophilic dibenzoate esters suggests low but measurable systemic absorption (e=1). (Sources: ECHA registration/substance pages; PubChem and manufacturer safety assessments.)
- Безопасен ли diethylene glycol/propylene glycol/dipropylene glycol dibenzoate при грудном вскармливании?
- Same rationale as pregnancy: the reaction mass has Repr.2 (H361) notifications at ECHA, so reproductive hazard is suspected (h=2). No data specifically demonstrating lactational transfer; mechanism unknown (m=1). Dermal absorption expected low but measurable for adults (e=1), so potential for small systemic exposure exists.
- Безопасен ли diethylene glycol/propylene glycol/dipropylene glycol dibenzoate для кожи малыша?
- Hazard classification (Repr.2/H361) for the reaction mass applies across sensitive populations in the absence of infant-specific safety data (h=2). Mechanistic data are limited (m=1). Exposure is increased for infants (0–3 yr) because immature skin has higher surface-area-to-body-weight and higher permeability; therefore exposure score is increased by +1 (adult e=1 → infant e=2). There are no infant-specific dermal toxicokinetic studies found.
- Как VeriMom оценивает diethylene glycol/propylene glycol/dipropylene glycol dibenzoate?
- VeriMom оценивает diethylene glycol/propylene glycol/dipropylene glycol dibenzoate в 27/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы diethylene glycol/propylene glycol/dipropylene glycol dibenzoate при беременности?
- См. наш список безопасных альтернатив diethylene glycol/propylene glycol/dipropylene glycol dibenzoate с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.