Стоит ли избегать dibutyl phthalate при беременности? | VeriMom

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FAQ

Безопасен ли dibutyl phthalate при беременности?

Dibutyl phthalate (DBP, CAS 84-74-2) has a harmonised CLP classification as H360 (may damage fertility or the unborn child) and is listed in the EU cosmetics Annex II (prohibited), indicating confirmed reproductive hazard; animal studies show male reproductive/developmental effects consistent with anti-androgenic mechanisms. (ECHA harmonised classification and Annex II listing; CIR and peer-reviewed animal literature support mechanism). Sources: https://echa.europa.eu/ (DBP brief/profile and C&L Annex VI harmonised H360), https://echa.europa.eu/cosmetics-prohibited-substances/-/legislationlist/substance/external/100.001.416, https://www.cir-safety.org/panelbook/safety-assessment-dibutyl-phthalate-diethyl-phthalate-and-dimethyl-phthalate-used-cosmetic

Безопасен ли dibutyl phthalate при грудном вскармливании?

Because DBP is a harmonised H360 substance (reproductive toxicant) and has demonstrated endocrine/anti-androgenic effects in animals, it is scored high for hazard and mechanism. DBP is lipophilic and human biomonitoring/authoritative assessments indicate systemic uptake and potential for body burden (supporting possible transfer to breastmilk), so exposure via systemic routes during lactation is rated higher than negligible. Sources: https://echa.europa.eu/brief-profile/-/briefprofile/100.001.416, https://www.epa.gov/assessing-and-managing-chemicals-under-tsca/risk-evaluation-dibutyl-phthalate-12-benzene, https://www.cir-safety.org/panelbook/safety-assessment-dibutyl-phthalate-diethyl-phthalate-and-dimethyl-phthalate-used-cosmetic

Безопасен ли dibutyl phthalate для кожи малыша?

Harmonised H360 applies irrespective of age (so hazard = 3). Mechanistic data (anti-androgenic/reprotoxic) are demonstrated in vivo in animals and remain relevant. For infant skin exposure, exposure score is increased by +1 relative to adult topical use because infants have higher surface-area-to-weight and more permeable skin and DBP is measurable/systemically absorbable; therefore exposure is moderate. Sources: https://echa.europa.eu/cosmetics-prohibited-substances/-/legislationlist/substance/external/100.001.416, https://echa.europa.eu/brief-profile/-/briefprofile/100.001.416, https://www.cir-safety.org/panelbook/safety-assessment-dibutyl-phthalate-diethyl-phthalate-and-dimethyl-phthalate-used-cosmetic

Как VeriMom оценивает dibutyl phthalate?

VeriMom оценивает dibutyl phthalate в 13/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы dibutyl phthalate при беременности?

См. наш список безопасных альтернатив dibutyl phthalate с аналогичной функцией и классификацией без известных рисков.