VeriMomVeriMom
HIGH RISK

Стоит ли избегать cyclotetrasiloxane при беременности? | VeriMom

Octamethylcyclotetrasiloxane (D4; CAS 556-67-2) has a harmonised CLP classification Repr. 2 (H361f) in ECHA’s Annex VI (CLH) and is listed with aquatic chronic H410; ECHA’s CLH and registration dossiers report reproductive effects in rodent studies and mechanistic papers describe possible endocrine-related modes of action, supporting a suspected reproductive hazard (h=2, m=2). Topical cosmetic exposure is generally lower than inhalation in animal studies; dermal absorption is measurable but limited for this volatile, lipophilic siloxane, so exposure from typical cosmetic use is scored low but measurable (e=1). Sources: ECHA CLH / brief profile; rodent reproductive studies and mechanistic reviews.

ECHA regulatory hazard statements

  • H361F

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли cyclotetrasiloxane при беременности?
Octamethylcyclotetrasiloxane (D4; CAS 556-67-2) has a harmonised CLP classification Repr. 2 (H361f) in ECHA’s Annex VI (CLH) and is listed with aquatic chronic H410; ECHA’s CLH and registration dossiers report reproductive effects in rodent studies and mechanistic papers describe possible endocrine-related modes of action, supporting a suspected reproductive hazard (h=2, m=2). Topical cosmetic exposure is generally lower than inhalation in animal studies; dermal absorption is measurable but limited for this volatile, lipophilic siloxane, so exposure from typical cosmetic use is scored low but measurable (e=1). Sources: ECHA CLH / brief profile; rodent reproductive studies and mechanistic reviews.
Безопасен ли cyclotetrasiloxane при грудном вскармливании?
Harmonised H361f (ECHA) and animal reproductive/developmental data justify treating D4 as a suspected reproductive toxicant (h=2) with demonstrated mechanistic evidence of endocrine-related effects in rodents (m=2). D4 is lipophilic and bioaccumulative in tissues and therefore has potential to partition into milk; for a breastfeeding parent systemic exposure and transfer to milk are plausible from repeated exposure—exposure scored moderate (e=2). Key regulatory/peer-reviewed sources report bioaccumulation and reproductive findings supporting this assessment.
Безопасен ли cyclotetrasiloxane для кожи малыша?
Because D4 carries a harmonised Repr. 2 classification (H361f) and rodent data indicate reproductive/developmental effects and endocrine-related modes of action, the hazard (h=2) and mechanism (m=2) are applied. Measurable dermal absorption for adults is reported (e=1); per your instruction baby-skin exposure is increased by +1 when adult absorption is measurable, giving e=2 for ages 0–3. Note: EU measures restrict/ban D4 in cosmetic products due to environmental and health concerns, reflecting the regulatory weight behind the hazard designation.
Как VeriMom оценивает cyclotetrasiloxane?
VeriMom оценивает cyclotetrasiloxane в 20/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
Какие безопасные альтернативы cyclotetrasiloxane при беременности?
См. наш список безопасных альтернатив cyclotetrasiloxane с аналогичной функцией и классификацией без известных рисков.

Проверь любой состав за 2 секунды

Скачай VeriMom бесплатно — отсканируй любой продукт и мгновенно получи оценку безопасности при беременности.

Медицинская оговорка

Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.

Получите полный доступ в приложении VeriMom