VeriMomСтоит ли избегать cyclamen aldehyde при беременности? | VeriMom
ECHA registration data and many supplier/SDS classifications list cyclamen aldehyde as Repr. Cat. 2 / H361 (suspected of damaging fertility or the unborn child) based on repeat-dose and reproductive findings in rats reported in the REACH dossier; however the published mechanistic work shows the male reproductive toxicity is tied to a species‑specific CoA‑conjugate metabolic pathway in rats. Topical cosmetic exposures would produce low but measurable systemic exposure in adults under typical use. (Sources: ECHA registration dossier; Tavares et al., PubMed).
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли cyclamen aldehyde при беременности?
- ECHA registration data and many supplier/SDS classifications list cyclamen aldehyde as Repr. Cat. 2 / H361 (suspected of damaging fertility or the unborn child) based on repeat-dose and reproductive findings in rats reported in the REACH dossier; however the published mechanistic work shows the male reproductive toxicity is tied to a species‑specific CoA‑conjugate metabolic pathway in rats. Topical cosmetic exposures would produce low but measurable systemic exposure in adults under typical use. (Sources: ECHA registration dossier; Tavares et al., PubMed).
- Безопасен ли cyclamen aldehyde при грудном вскармливании?
- Given the Repr. Cat.2/H361 classification reported in dossiers and the demonstrated metabolic mechanism causing male rat reproductive effects, the conservative hazard score is 2 (suspected). There are no human lactation/breastmilk transfer data; systemic exposure from topical use is expected to be low but measurable, so breastfeeding exposure is possible though not quantified (see ECHA dossier and animal/mechanistic study).
- Безопасен ли cyclamen aldehyde для кожи малыша?
- Hazard and mechanism scores are driven by the same animal/mechanistic evidence (suspected reproductive toxicant with a demonstrated rat metabolic pathway). Exposure score is increased by +1 for baby skin (per your rubric) because topical use on infants gives higher per‑kg absorption and immature barrier — while direct infant-specific toxicology is lacking, absorption is plausibly higher than adults. No infant developmental or dermal‑transfer studies were located.
- Как VeriMom оценивает cyclamen aldehyde?
- VeriMom оценивает cyclamen aldehyde в 20/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы cyclamen aldehyde при беременности?
- См. наш список безопасных альтернатив cyclamen aldehyde с аналогичной функцией и классификацией без известных рисков.
Проверь любой состав за 2 секунды
Скачай VeriMom бесплатно — отсканируй любой продукт и мгновенно получи оценку безопасности при беременности.
Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.