Стоит ли избегать cupric chloride при беременности? | VeriMom
ECHA lists cupric (copper(II)) chloride (CAS 7447-39-4) with a harmonised classification including H361 (suspected of damaging fertility or the unborn child), which supports a hazard score of 2. Peer‑reviewed studies show mechanistic plausibility for copper‑mediated placental/embryonic injury (e.g., placental ‘cuproptosis’ and other reproductive effects in animal studies), supporting a mechanism score of 2. For typical topical cosmetic use dermal absorption of dissolved copper ions is low but not negligible, so exposure from cosmetics is scored as 1. (Sources: ECHA brief profile; PubMed studies on copper and placental/reproductive effects).
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли cupric chloride при беременности?
- ECHA lists cupric (copper(II)) chloride (CAS 7447-39-4) with a harmonised classification including H361 (suspected of damaging fertility or the unborn child), which supports a hazard score of 2. Peer‑reviewed studies show mechanistic plausibility for copper‑mediated placental/embryonic injury (e.g., placental ‘cuproptosis’ and other reproductive effects in animal studies), supporting a mechanism score of 2. For typical topical cosmetic use dermal absorption of dissolved copper ions is low but not negligible, so exposure from cosmetics is scored as 1. (Sources: ECHA brief profile; PubMed studies on copper and placental/reproductive effects).
- Безопасен ли cupric chloride при грудном вскармливании?
- Harmonised H361 classification (ECHA) indicates suspected reproductive/developmental hazard, so h=2. Mechanistic evidence for copper affecting placental/early development supports m=2. For topical use, systemic absorption is expected to be low but measurable (e=1); parenteral/medicinal forms of copper note caution in nursing in product labeling, but there is no high‑quality human milk transfer data for cosmetic topical use.
- Безопасен ли cupric chloride для кожи малыша?
- Hazard (h=2) and mechanism (m=2) are not increased in the absence of infant‑specific toxicity data, but exposure (e) is increased by +1 for 0–3 y skin because infant skin has higher surface‑area‑to‑weight and an immature barrier; therefore e=2. There is no specific evidence that cosmetic topical use of cupric chloride causes infant developmental effects, but the harmonised classification and copper reproductive biology motivate caution.
- Как VeriMom оценивает cupric chloride?
- VeriMom оценивает cupric chloride в 20/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы cupric chloride при беременности?
- См. наш список безопасных альтернатив cupric chloride с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.