HIGH RISK
Стоит ли избегать cobalt chloride при беременности? | VeriMom
Reviewed by VeriMom Editorial Team · Last reviewed
ECHA regulatory hazard statements
- •H350I
- •H360F
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Authoritative references used to score this ingredient.
Безопасные альтернативы cobalt chloride при беременности | VeriMom
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FAQ
- Безопасен ли cobalt chloride при беременности?
- Cobalt(II) chloride has harmonised CLP classifications for carcinogenicity and reproductive toxicity in the EU (H350i, H360F and related entries for cobalt compounds in Annex VI) which per your scoring rules mandates h=3. Multiple animal studies report reproductive and developmental effects (reduced sperm/testis effects, embryolethality and developmental delays) after systemic exposure to cobalt salts, supporting a demonstrated mechanism of reproductive toxicity rather than a purely theoretical concern. Topical cosmetic exposure would generally give low but measurable systemic exposure (so e=1) unless formulations or damaged skin markedly increase absorption. Sources: ECHA harmonised classification and dossiers; animal reproductive studies and reviews (PubMed/ATSDR).
- Безопасен ли cobalt chloride при грудном вскармливании?
- Harmonised EU classification (H360F, H350i etc.) and animal data showing systemic reproductive/developmental toxicity support h=3. Mechanistic data indicate demonstrated systemic effects (e.g., testicular/sperm effects, embryotoxicity) consistent with m=2. For breastfeeding, dermal cosmetic use would likely give low systemic exposure (e=1); cobalt is systemically bioavailable when ingested or absorbed and can distribute in body tissues, so transfer to milk is plausible though likely low at typical topical-use exposures.
- Безопасен ли cobalt chloride для кожи малыша?
- Hazard (h=3) follows the harmonised CLP reproductive/CMR classifications for cobalt compounds (H360F/H350i/H341). The mechanism is supported by animal reproductive/developmental studies showing demonstrated systemic and developmental effects (m=2). Exposure score is increased by +1 for infants versus adult because (a) cobalt salts are water‑soluble ionic metals with measurable dermal absorption under some conditions, and (b) infant skin has higher surface-area-to-body-weight and an immature barrier — so if adult e=1, infant e=2.
- Как VeriMom оценивает cobalt chloride?
- VeriMom оценивает cobalt chloride в 20/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы cobalt chloride при беременности?
- См. наш список безопасных альтернатив cobalt chloride с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.