Стоит ли избегать captan при беременности? | VeriMom

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли captan при беременности?

Captan has been flagged as a suspected reproductive hazard (H361-level concern reported in regulatory dossiers and SDSs) and animal/experimental studies report effects on reproductive tissues (mouse ovarian disruption, decreased fertility in some rodent studies). Mechanistic studies show mitochondrial dysfunction, oxidative stress, DNA damage and apoptosis in oocytes (demonstrated in vivo/in vitro). For topical/cosmetic use dermal absorption is reported to be very low (<1% per hour in regulatory assessments and human toxicokinetic studies), so exposure from cosmetic topical use is low but measurable. Sources: PubMed (mouse ovarian study), EPA/NPIC summaries, human toxicokinetic/dermal studies and occupational assessments.

Безопасен ли captan при грудном вскармливании?

Hazard and mechanism same rationale as for pregnancy (animal reproductive effects and mechanistic evidence). Dermal absorption from topical application is low (human toxicokinetic data and EPA/NPIC assessments), and while captan metabolites have been detected in animal milk in some studies, human milk transfer data are sparse — exposure via maternal topical use is therefore low but measurable. Sources: NPIC/EPA summaries, human dermal toxicokinetic study, animal milk data.

Безопасен ли captan для кожи малыша?

Hazard (H361-level/suspected reproductive/developmental effects) and mechanistic findings apply (animal reproductive/ovarian effects, demonstrated oocyte toxicity). Dermal absorption for adults is low but measurable; per your scoring rules, infant skin exposure is increased by +1 because infant skin has higher permeability and higher surface-area-to-weight, so exposure for a baby (0–3 yr) is moderate. There is no infant-specific evidence to raise hazard or mechanism scores beyond the adult evidence. Sources: human dermal/tokinetic studies, EPA/NPIC, PubMed reproductive/toxicology studies.

Как VeriMom оценивает captan?

VeriMom оценивает captan в 20/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы captan при беременности?

См. наш список безопасных альтернатив captan с аналогичной функцией и классификацией без известных рисков.