VeriMomСтоит ли избегать caffeic acid при беременности? | VeriMom
Animal reproductive/developmental study in mice reported effects on embryo implantation at 5 and 150 mg/kg/day and reduced fetal weight at 150 mg/kg/day (NOAEL 0.15 mg/kg/day), supporting a suspected reproductive hazard (animal evidence). ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/30366071/)) Supplier safety data sheets also state classification as Repr. Cat.2 (H361d), though these appear to be company/ SDS classifications rather than a confirmed harmonised CLP entry. ([static.cymitquimica.com](https://static.cymitquimica.com/products/54/pdf/sds-BIB6021.pdf?utm_source=openai))
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли caffeic acid при беременности?
- Animal reproductive/developmental study in mice reported effects on embryo implantation at 5 and 150 mg/kg/day and reduced fetal weight at 150 mg/kg/day (NOAEL 0.15 mg/kg/day), supporting a suspected reproductive hazard (animal evidence). ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/30366071/)) Supplier safety data sheets also state classification as Repr. Cat.2 (H361d), though these appear to be company/ SDS classifications rather than a confirmed harmonised CLP entry. ([static.cymitquimica.com](https://static.cymitquimica.com/products/54/pdf/sds-BIB6021.pdf?utm_source=openai))
- Безопасен ли caffeic acid при грудном вскармливании?
- No human lactation data located; animal reproductive/developmental data indicate reproductive/developmental effects, so breastfeeding is assigned the same hazard/ mechanism tier as pregnancy in the absence of breastfeeding-specific data. Topical cosmetic use is expected to give low but measurable systemic exposure in adults. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/30366071/))
- Безопасен ли caffeic acid для кожи малыша?
- Hazard and mechanism are driven by the mouse developmental study (suspected reproductive/developmental effects). Per your rules, exposure score is increased by +1 for baby skin versus adult because caffeic acid has measurable absorption potential when systemically bioavailable; therefore exposure for 0–3 yr skin is moderate. No infant-specific toxicity studies were found. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/30366071/))
- Как VeriMom оценивает caffeic acid?
- VeriMom оценивает caffeic acid в 20/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы caffeic acid при беременности?
- См. наш список безопасных альтернатив caffeic acid с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.