Стоит ли избегать butylated xylenol при беременности? | VeriMom

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли butylated xylenol при беременности?

OECD SIDS (Japanese GLP OECD TG 422 study) reports reproductive/developmental effects in rats at 150 mg/kg/day (loss of litters, maternal deaths) with a reproductive NOEL of 30 mg/kg/day; no mechanistic reproductive data were located. No evidence of consumer/cosmetic topical exposure scenarios was found in the SIDS, and ECHA registration pages list industrial/antioxidant uses rather than cosmetic uses, so expected dermal exposure from cosmetics is not documented (exposure scored as 0). (Sources: OECD SIDS; ECHA registration dossier).

Безопасен ли butylated xylenol при грудном вскармливании?

Same basis as pregnancy: the OECD combined repeat-dose/reproductive screening study showed pup viability losses and maternal fatalities at 150 mg/kg/day (reproductive NOEL 30 mg/kg/day); no breastfeeding-specific toxicokinetic or milk-transfer data were found, and no consumer dermal exposure data for cosmetic use were identified (exposure scored 0). (Sources: OECD SIDS; ECHA registration dossier).

Безопасен ли butylated xylenol для кожи малыша?

Hazard scoring follows the animal reproductive findings (OECD SIDS) — suspected reproductive/developmental hazard. No infant-specific mechanistic or toxicokinetic data were located. Although consumer dermal exposure for cosmetics was not documented, infant skin has higher absorption potential; therefore exposure for baby skin is increased by +1 versus adult (adult exposure scored 0 → baby exposure scored 1). (Sources: OECD SIDS; ECHA registration/registration dossier).

Как VeriMom оценивает butylated xylenol?

VeriMom оценивает butylated xylenol в 39/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы butylated xylenol при беременности?

См. наш список безопасных альтернатив butylated xylenol с аналогичной функцией и классификацией без известных рисков.