Стоит ли избегать butadiene при беременности? | VeriMom
1,3-Butadiene (CAS 106-99-0) has harmonised EU/ECHA hazard data and is classified as a carcinogen and mutagen with animal reproductive/developmental toxicity reported; mechanistic work shows reactive epoxide metabolites that are mutagenic, supporting a demonstrated mechanism relevant to reproduction/carcinogenesis (ECHA, IARC, NTP, PubMed). Topical cosmetic exposure is not a typical use form (volatile monomer/gas), so dermal exposure from cosmetics would be negligible. Sources: ECHA substance/brief profile; IARC monograph; NTP and peer-reviewed reproductive reviews (links in sources).
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли butadiene при беременности?
- 1,3-Butadiene (CAS 106-99-0) has harmonised EU/ECHA hazard data and is classified as a carcinogen and mutagen with animal reproductive/developmental toxicity reported; mechanistic work shows reactive epoxide metabolites that are mutagenic, supporting a demonstrated mechanism relevant to reproduction/carcinogenesis (ECHA, IARC, NTP, PubMed). Topical cosmetic exposure is not a typical use form (volatile monomer/gas), so dermal exposure from cosmetics would be negligible. Sources: ECHA substance/brief profile; IARC monograph; NTP and peer-reviewed reproductive reviews (links in sources).
- Безопасен ли butadiene при грудном вскармливании?
- Same hazard basis as pregnancy: harmonised classification and multiple authoritative reviews identify carcinogenicity, mutagenicity and animal reproductive/developmental effects; mechanism via reactive epoxide metabolites is demonstrated. Cosmetic/topical exposure is unlikely for the gaseous monomer so dermal absorption from cosmetic use is negligible. See sources for evidence.
- Безопасен ли butadiene для кожи малыша?
- Hazard and mechanism are the same (harmonised carcinogen/mutagen, animal reproductive/developmental toxicity, reactive metabolites). 1,3-Butadiene is a volatile industrial monomer not used as a cosmetic ingredient in finished products (so dermal exposure from cosmetics is effectively negligible); therefore exposure (e) from cosmetic use to infants is scored 0. If an actual cosmetic product contained residual monomer (extremely unlikely), infant exposure and absorption concerns would be higher. See sources for evidence.
- Как VeriMom оценивает butadiene?
- VeriMom оценивает butadiene в 27/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы butadiene при беременности?
- См. наш список безопасных альтернатив butadiene с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.