Стоит ли избегать bishydroxyethyl biscetyl malonamide при беременности? | VeriMom

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли bishydroxyethyl biscetyl malonamide при беременности?

The ingredient (INCI: Bishydroxyethyl Biscetyl Malonamide; CAS 149591-38-8, AKA Questamide H) is listed in Annex II (substances prohibited in cosmetics) of the EU Cosmetic Products Regulation (Regulation (EC) No 1223/2009; entry no. 1243), which reflects its removal from cosmetic use because of CMR concerns (the EU measures that added CMR-classified/suspect CMR substances to Annex II cite reproductive hazard as a reason). I could not locate a separate harmonised CLP entry on the ECHA C&L inventory that explicitly shows a harmonised H361f classification; however, the EU cosmetics regulatory listing is an authoritative regulatory action indicating suspected reproductive hazard. No published SCCS or CIR safety assessment or peer‑reviewed reproductive/toxicity studies specific to this substance were found to allow more precise hazard or mechanistic assignment.

Безопасен ли bishydroxyethyl biscetyl malonamide при грудном вскармливании?

Same rationale as for pregnancy: regulatory prohibition from use in cosmetics in the EU due to CMR concerns (Annex II, Reg. 1223/2009 entry 1243). No data were found documenting milk transfer or mechanism-of-action relevant to lactation, so mechanistic score remains 0; exposure is assigned as low but measurable for topical adult use.

Безопасен ли bishydroxyethyl biscetyl malonamide для кожи малыша?

Regulatory prohibition for cosmetic use (EU Annex II) implies suspected reproductive/CMR concern that supports caution for infant use. Dermal exposure for infants is expected to be higher than adults due to immature barrier and higher surface-area-to-weight; because there are no infant-specific absorption studies, I increased exposure by +1 per your rules. No infant-specific toxicity studies were located.

Как VeriMom оценивает bishydroxyethyl biscetyl malonamide?

VeriMom оценивает bishydroxyethyl biscetyl malonamide в 33/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы bishydroxyethyl biscetyl malonamide при беременности?

См. наш список безопасных альтернатив bishydroxyethyl biscetyl malonamide с аналогичной функцией и классификацией без известных рисков.