VeriMomСтоит ли избегать ammonium vanadate при беременности? | VeriMom
Animal and review literature report reproductive and developmental toxicity after maternal exposure to vanadium compounds including ammonium metavanadate (embryotoxicity, increased fetal mortality and malformations). ECHA REACH registration dossiers and published reviews summarize these findings. Harmonised CLP proposals/intentions have been recorded for ammonium trioxovanadate but a final Annex VI harmonised H360 classification was not found; however H361 (suspected) is reported in some chemical listings/SDS. Given animal evidence and regulatory dossiers, hazard = suspected (H361-level). Low but measurable systemic exposure is expected from topical use of inorganic vanadates (so exposure scoring =1).
ECHA regulatory hazard statements
- •H361
- •H361D
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли ammonium vanadate при беременности?
- Animal and review literature report reproductive and developmental toxicity after maternal exposure to vanadium compounds including ammonium metavanadate (embryotoxicity, increased fetal mortality and malformations). ECHA REACH registration dossiers and published reviews summarize these findings. Harmonised CLP proposals/intentions have been recorded for ammonium trioxovanadate but a final Annex VI harmonised H360 classification was not found; however H361 (suspected) is reported in some chemical listings/SDS. Given animal evidence and regulatory dossiers, hazard = suspected (H361-level). Low but measurable systemic exposure is expected from topical use of inorganic vanadates (so exposure scoring =1).
- Безопасен ли ammonium vanadate при грудном вскармливании?
- Vanadium compounds are reported to be systemically bioavailable after absorption and have shown developmental/offspring effects in animal studies; placental/transplacental transfer and systemic distribution have been reported for vanadates, supporting potential transfer into milk (mechanism demonstrated in animal work). Topical cosmetic use would likely give low but measurable systemic exposure (e=1). Therefore breastfeeding is assigned the same suspected reproductive/developmental concern (h=2, m=2).
- Безопасен ли ammonium vanadate для кожи малыша?
- No infant-specific toxicity studies were identified. Parent compound (vanadium/vanadate) shows developmental toxicity in animals. Because infant skin has higher permeability/surface-area-to-weight, exposure score is increased by +1 (adult e=1 → baby e=2). Hazard and mechanism are not increased without infant-specific evidence, so h=2, m=2. Topical use on baby skin could therefore give greater relative exposure and is not recommended.
- Как VeriMom оценивает ammonium vanadate?
- VeriMom оценивает ammonium vanadate в 20/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы ammonium vanadate при беременности?
- См. наш список безопасных альтернатив ammonium vanadate с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.