Стоит ли избегать adipic acid dihydrazide при беременности? | VeriMom

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Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли adipic acid dihydrazide при беременности?

Authoritative reviews (CIR final report) and ECHA registration data do not identify adipic acid dihydrazide as a confirmed reproductive/developmental toxicant; an ECHA prenatal developmental study reported a maternal and developmental NOAEL of 100 mg/kg and concluded the substance need not be classified as a developmental toxicant. Many supplier SDSs list H361 as a notified/company classification, but no EU-harmonised (Annex VI) CLH for H360/H361 was found; self-notifications alone do not establish harmonised reproductive hazard. (Sources: CIR review; ECHA registration dossier/study; multiple SDSs noting company H361 notifications).

Безопасен ли adipic acid dihydrazide при грудном вскармливании?

There is no evidence in the available literature or regulatory dossiers of lactation-specific toxicity or of a mechanism predicting transfer into breastmilk. With topical cosmetic use and the absence of data indicating high dermal/systemic absorption, systemic exposure (and therefore lactational exposure) is expected to be negligible. (Sources: ECHA dossier, CIR summary, no PubMed studies showing lactational transfer).

Безопасен ли adipic acid dihydrazide для кожи малыша?

No infant-specific reproductive/ developmental hazard data were identified. Dermal exposure for infants is a pragmatic concern because infant skin has a higher surface-area-to-weight ratio and immature barrier; while there are no data showing high dermal absorption for this ingredient, exposure scoring is increased by +1 for baby skin compared with adult topical use to account for the more vulnerable infant barrier. No studies show specific adverse effects in 0–3 y olds. (Sources: ECHA registration dossier; CIR; general toxicology principles).

Как VeriMom оценивает adipic acid dihydrazide?

VeriMom оценивает adipic acid dihydrazide в 39/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы adipic acid dihydrazide при беременности?

См. наш список безопасных альтернатив adipic acid dihydrazide с аналогичной функцией и классификацией без известных рисков.