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Стоит ли избегать acrylonitrile при беременности? | VeriMom

Acrylonitrile carries harmonised CLP flags for reproductive toxicity (H361) per ECHA’s substance profile, which makes it a suspected reproductive hazard (h=2). Animal and mechanistic studies and weight-of-evidence reviews report developmental/reproductive findings and genotoxicity consistent with a demonstrated (but not fully elucidated, non-human) mechanism (m=2). For cosmetic topical use exposure is effectively negligible because acrylonitrile is not an approved cosmetic ingredient and is listed in regulatory contexts restricting use, so consumer topical exposure from intentionally formulated cosmetics is expected to be negligible (e=0).

ECHA regulatory hazard statements

  • H350

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли acrylonitrile при беременности?
Acrylonitrile carries harmonised CLP flags for reproductive toxicity (H361) per ECHA’s substance profile, which makes it a suspected reproductive hazard (h=2). Animal and mechanistic studies and weight-of-evidence reviews report developmental/reproductive findings and genotoxicity consistent with a demonstrated (but not fully elucidated, non-human) mechanism (m=2). For cosmetic topical use exposure is effectively negligible because acrylonitrile is not an approved cosmetic ingredient and is listed in regulatory contexts restricting use, so consumer topical exposure from intentionally formulated cosmetics is expected to be negligible (e=0).
Безопасен ли acrylonitrile при грудном вскармливании?
Same basis as pregnancy: harmonised/suspected reproductive classification (H361) and animal/experimental evidence indicate possible effects relevant to breastfeeding (h=2) with demonstrated mechanistic concerns in toxicology literature (m=2). Exposure from cosmetic topical products is negligible because it is not a permitted cosmetic ingredient in regulated markets and would not be intentionally present (e=0).
Безопасен ли acrylonitrile для кожи малыша?
Hazard and mechanistic scoring mirror pregnancy/breastfeeding because the substance is suspected for reproductive/developmental effects (H361) and has animal/experimental evidence (h=2, m=2). Adult topical cosmetic exposure is expected to be negligible (no allowed use), so infant dermal exposure from cosmetics is likewise negligible (e=0); therefore no infant-specific exposure increment was applied. If acrylonitrile were present in a product used on infant skin, concern would be elevated due to its toxicity and infants’ greater vulnerability.
Как VeriMom оценивает acrylonitrile?
VeriMom оценивает acrylonitrile в 27/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
Какие безопасные альтернативы acrylonitrile при беременности?
См. наш список безопасных альтернатив acrylonitrile с аналогичной функцией и классификацией без известных рисков.

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Медицинская оговорка

Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.

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