Стоит ли избегать acrolein при беременности? | VeriMom

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли acrolein при беременности?

Acrolein (CAS 107-02-8) is a reactive α,β‑unsaturated aldehyde with animal data showing reproductive/developmental effects (reduced pup weights, effects on fetal/testicular endpoints) in rodents at systemic/toxic doses; therefore it is a suspected reproductive hazard based on animal evidence. Mechanistic studies demonstrate mitochondrial/glycolytic disruption and oocyte/embryo toxicity in vitro and in vivo, supporting a demonstrated mechanism. Topical/cosmetic exposure would generally give low but measurable systemic exposure if present because acrolein is small and reactive, but routine cosmetic formulations do not commonly include free acrolein; therefore exposure from intended cosmetic topical use is judged low.

Безопасен ли acrolein при грудном вскармливании?

Same hazard and mechanism considerations apply for lactation: animal reproductive/developmental effects and mechanistic evidence indicate a suspected reproductive hazard. For cosmetic topical use systemic absorption is expected to be low but measurable, so transfer into breastmilk could theoretically occur if significant systemic levels were reached, but typical cosmetic exposures are low.

Безопасен ли acrolein для кожи малыша?

Hazard and mechanism same as for adults (suspected reproductive/developmental hazard with demonstrated mitochondrial/oocyte effects). Exposure score is increased by +1 for infants (per your rule) because acrolein has measurable dermal effects (it is skin‑corrosive/irritant and a small reactive molecule) so infants’ higher surface‑area‑to‑weight and immature barrier raise likely systemic uptake from topical application above adult levels.

Как VeriMom оценивает acrolein?

VeriMom оценивает acrolein в 20/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы acrolein при беременности?

См. наш список безопасных альтернатив acrolein с аналогичной функцией и классификацией без известных рисков.