Стоит ли избегать acetanilid при беременности? | VeriMom

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли acetanilid при беременности?

Animal reproductive/developmental studies (OECD SIDS / repeated-dose and reproduction studies) report reproductive/developmental effects and NOAELs in rats; several manufacturer SDS also list H361 (suspected of damaging fertility or the unborn child), so acetanilide is reasonably suspected from animal data. Mechanistic data are limited — metabolism to aniline/phenolic metabolites is known (theoretical concern) but there is no well-characterised placental-transfer or endocrine-disruption mechanism for acetanilide in humans. Topical cosmetic absorption is expected to be low but measurable (low log Kow, used at low concentrations), so exposure from typical topical use is low but non‑zero.

Безопасен ли acetanilid при грудном вскармливании?

Same animal evidence that supports a suspected reproductive/developmental hazard applies to lactation context (no human breastfeeding-specific safety data). Mechanistic concerns are theoretical (metabolism to aniline); topical absorption is likely low but measurable so maternal systemic exposure from cosmetics could be low but not zero, with potential for transfer into milk not well studied.

Безопасен ли acetanilid для кожи малыша?

Hazard scoring follows the animal evidence (suspected reproductive/developmental hazard). Mechanistic evidence remains theoretical. Exposure score increased by +1 for infants (per instructions) because baby skin has higher surface-area-to-weight and an immature barrier and acetanilide has measurable (though limited) dermal absorption; thus infant exposure from topical products is moderate rather than low.

Как VeriMom оценивает acetanilid?

VeriMom оценивает acetanilid в 27/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы acetanilid при беременности?

См. наш список безопасных альтернатив acetanilid с аналогичной функцией и классификацией без известных рисков.