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Стоит ли избегать acetaldehyde при беременности? | VeriMom

Regulatory and experimental evidence indicates reproductive/developmental concern but not an established human teratogen at cosmetic exposures. The SCCNFP (2004) noted acetaldehyde is a mutagen/carcinogen but concluded cosmetic dermal exposures are very low and gave a use limit; experimental studies show embryotoxic/teratogenic effects in vitro and acetaldehyde is implicated as a metabolite in fetal alcohol syndrome. ECHA substance pages and registration dossiers list mutagenic/carcinogenic hazards; harmonised CLP entries for acetaldehyde centre on Carc./Muta. (and proposals/consultations on reproductive classification exist) but a definitive harmonised H360 label for reproductive toxicity is not consistently published across ECHA outputs searched. Citations: SCCNFP (2004) opinion; PubMed teratogenicity study; ECHA substance/registration information; EWG ingredient summary.

ECHA regulatory hazard statements

  • H350

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FAQ

Безопасен ли acetaldehyde при беременности?
Regulatory and experimental evidence indicates reproductive/developmental concern but not an established human teratogen at cosmetic exposures. The SCCNFP (2004) noted acetaldehyde is a mutagen/carcinogen but concluded cosmetic dermal exposures are very low and gave a use limit; experimental studies show embryotoxic/teratogenic effects in vitro and acetaldehyde is implicated as a metabolite in fetal alcohol syndrome. ECHA substance pages and registration dossiers list mutagenic/carcinogenic hazards; harmonised CLP entries for acetaldehyde centre on Carc./Muta. (and proposals/consultations on reproductive classification exist) but a definitive harmonised H360 label for reproductive toxicity is not consistently published across ECHA outputs searched. Citations: SCCNFP (2004) opinion; PubMed teratogenicity study; ECHA substance/registration information; EWG ingredient summary.
Безопасен ли acetaldehyde при грудном вскармливании?
No clear human lactation-transfer data were found. Acetaldehyde has reproductive/developmental hazard evidence (see pregnancy explanation), but direct evidence for transfer into breastmilk or breastmilk-mediated infant toxicity is lacking. Mechanistic support for concern is present but direct demonstrated lactational transfer data are not found; topical cosmetic exposures to an adult nursing parent are expected to produce low systemic exposure. Citations: ECHA substance pages; SCCNFP (2004); PubMed.
Безопасен ли acetaldehyde для кожи малыша?
Infant skin has higher surface-area-to-weight and less mature barrier; where adult topical exposure is measurable, infant dermal exposure is plausibly higher. Acetaldehyde has demonstrated embryotoxic/teratogenic activity in experimental systems (supporting hazard and mechanism); the SCCNFP concluded dermal consumer exposure from fragranced cosmetics is very low but assumed 100% absorption when calculating internal dose. Because absorption is measurable, exposure for 0–3 yr skin is increased by one band. Citations: SCCNFP (2004) exposure assessment; PubMed teratogenicity literature; ECHA substance info.
Как VeriMom оценивает acetaldehyde?
VeriMom оценивает acetaldehyde в 20/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
Какие безопасные альтернативы acetaldehyde при беременности?
См. наш список безопасных альтернатив acetaldehyde с аналогичной функцией и классификацией без известных рисков.

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Медицинская оговорка

Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.

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