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Стоит ли избегать 4,4'-isopropylidenediphenol при беременности? | VeriMom

Bisphenol A (4,4'-isopropylidenediphenol) has a harmonised CLP classification including Repr. 1B (H360F) under ECHA Annex VI, which by calibration requires h=3. BPA is a demonstrated endocrine disruptor with evidence of placental/fetal transfer and fetal effects in animal and human-focused reviews (mechanism score m=2). For topical cosmetic use, dermal absorption is measurable but generally lower than dietary routes, so exposure for pregnant adults is scored as low-measurable (e=1).

ECHA regulatory hazard statements

  • H360F

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли 4,4'-isopropylidenediphenol при беременности?
Bisphenol A (4,4'-isopropylidenediphenol) has a harmonised CLP classification including Repr. 1B (H360F) under ECHA Annex VI, which by calibration requires h=3. BPA is a demonstrated endocrine disruptor with evidence of placental/fetal transfer and fetal effects in animal and human-focused reviews (mechanism score m=2). For topical cosmetic use, dermal absorption is measurable but generally lower than dietary routes, so exposure for pregnant adults is scored as low-measurable (e=1).
Безопасен ли 4,4'-isopropylidenediphenol при грудном вскармливании?
Harmonised Repr.1B (H360F) applies to BPA so h=3. BPA demonstrates endocrine activity and is transferred into breast milk; human biomonitoring and review literature document detectable BPA in breast milk and infant exposure (m=2). Because breastfeeding transfers systemic BPA to the infant (measured in milk and infant urine), exposure is moderate (e=2).
Безопасен ли 4,4'-isopropylidenediphenol для кожи малыша?
The parent compound BPA carries harmonised H360F → h=3. Mechanistic evidence of endocrine activity and developmental effects supports m=2. For topical exposure to infants (0–3 yr) the exposure score is increased by +1 relative to adults due to immature skin and higher surface-area-to-weight; given measurable dermal absorption in adults (used in cosmetics) adult e=1 → infant e=2.
Как VeriMom оценивает 4,4'-isopropylidenediphenol?
VeriMom оценивает 4,4'-isopropylidenediphenol в 20/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
Какие безопасные альтернативы 4,4'-isopropylidenediphenol при беременности?
См. наш список безопасных альтернатив 4,4'-isopropylidenediphenol с аналогичной функцией и классификацией без известных рисков.

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Медицинская оговорка

Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.

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