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Стоит ли избегать 3-(p-cumenyl)-2-methylpropionaldehyde при беременности? | VeriMom

Multiple REACH/ECHA registration pages and company C&L notifications list reproductive-toxicity warning code H361 (Suspected of damaging fertility or the unborn child) for 3-(p-cumenyl)-2-methylpropionaldehyde, and a dedicated fragrance ingredient safety assessment (RIFM) exists but does not establish a harmonised Annex VI classification. Under the provided calibration H361 → h=2. Mechanistic data for reproductive toxicity are not well‑documented (hence m=1 = theoretical/limited). Dermal exposure from cosmetics is expected to be low but measurable for an aromatic aldehyde used as a fragrance (e=1). Sources: ECHA substance pages; RIFM (PubMed).

ECHA regulatory hazard statements

  • H361

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли 3-(p-cumenyl)-2-methylpropionaldehyde при беременности?
Multiple REACH/ECHA registration pages and company C&L notifications list reproductive-toxicity warning code H361 (Suspected of damaging fertility or the unborn child) for 3-(p-cumenyl)-2-methylpropionaldehyde, and a dedicated fragrance ingredient safety assessment (RIFM) exists but does not establish a harmonised Annex VI classification. Under the provided calibration H361 → h=2. Mechanistic data for reproductive toxicity are not well‑documented (hence m=1 = theoretical/limited). Dermal exposure from cosmetics is expected to be low but measurable for an aromatic aldehyde used as a fragrance (e=1). Sources: ECHA substance pages; RIFM (PubMed).
Безопасен ли 3-(p-cumenyl)-2-methylpropionaldehyde при грудном вскармливании?
Same basis as pregnancy: substance is flagged in ECHA/registration/C&L entries with H361 notifications and a RIFM safety assessment exists. No clear, publicly available data showing proven placental/milk transfer or a defined reproductive mechanism; systemic exposure after topical use is expected low but non‑zero, so breastfeeding concern follows the pregnancy score (h=2, m=1, e=1).
Безопасен ли 3-(p-cumenyl)-2-methylpropionaldehyde для кожи малыша?
Hazard scoring follows pregnancy/breastfeeding because of the H361 flag/notifications (h=2) and absence of a demonstrated mechanism (m=1). Exposure (e) is increased by +1 for infants (per instructions) because the compound is a fragrance aldehyde with measurable absorption in consumer contexts; therefore adult e=1 → baby e=2. No infant‑specific safety data were located. (See RIFM and ECHA registration pages.)
Как VeriMom оценивает 3-(p-cumenyl)-2-methylpropionaldehyde?
VeriMom оценивает 3-(p-cumenyl)-2-methylpropionaldehyde в 27/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
Какие безопасные альтернативы 3-(p-cumenyl)-2-methylpropionaldehyde при беременности?
См. наш список безопасных альтернатив 3-(p-cumenyl)-2-methylpropionaldehyde с аналогичной функцией и классификацией без известных рисков.

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Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.

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