VeriMomСтоит ли избегать 2-methyl-3-buten-2-ol при беременности? | VeriMom
No EU harmonised (Annex VI) reproductive classification was found for 2‑methyl‑3‑buten‑2‑ol (CAS 115‑18‑4) and authoritative safety reviews (RIFM peer‑reviewed assessment) identify a NOAEL of 50 mg/kg/day from repeat/developmental/reproductive studies and conclude current use is supported; supplier SDS entries that list H361 appear to be company self‑classifications, which per your rules do not by themselves raise h. Physicochemical data (log Kow ≈1.1, high water solubility) and RIFM exposure assessment support low but measurable systemic exposure from topical use, so exposure (e) is scored 1 for pregnancy (adult topical exposure).
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли 2-methyl-3-buten-2-ol при беременности?
- No EU harmonised (Annex VI) reproductive classification was found for 2‑methyl‑3‑buten‑2‑ol (CAS 115‑18‑4) and authoritative safety reviews (RIFM peer‑reviewed assessment) identify a NOAEL of 50 mg/kg/day from repeat/developmental/reproductive studies and conclude current use is supported; supplier SDS entries that list H361 appear to be company self‑classifications, which per your rules do not by themselves raise h. Physicochemical data (log Kow ≈1.1, high water solubility) and RIFM exposure assessment support low but measurable systemic exposure from topical use, so exposure (e) is scored 1 for pregnancy (adult topical exposure).
- Безопасен ли 2-methyl-3-buten-2-ol при грудном вскармливании?
- No evidence found of a specific lactation/transfer hazard or a harmonised reproductive hazard. Given low‑to‑moderate systemic absorption predicted from dermal exposure (RIFM assessment), maternal systemic exposure is expected to be low but measurable; therefore exposure for breastfeeding is scored 1. No mechanistic or human lactation data were identified.
- Безопасен ли 2-methyl-3-buten-2-ol для кожи малыша?
- No infant‑specific reproductive or developmental hazard data were found and authoritative reviews do not flag the substance as a reproductive teratogen. Because infant skin has higher surface‑area‑to‑weight and an immature barrier, the exposure score is increased by +1 versus adult (adult e=1 → baby e=2) reflecting higher potential dermal absorption on 0–3 yr skin, though no infant‑specific absorption studies were identified.
- Как VeriMom оценивает 2-methyl-3-buten-2-ol?
- VeriMom оценивает 2-methyl-3-buten-2-ol в 33/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы 2-methyl-3-buten-2-ol при беременности?
- См. наш список безопасных альтернатив 2-methyl-3-buten-2-ol с аналогичной функцией и классификацией без известных рисков.
Проверь любой состав за 2 секунды
Скачай VeriMom бесплатно — отсканируй любой продукт и мгновенно получи оценку безопасности при беременности.
Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.