Question 1

Is (astragalus membranaceus/glycyrrhiza uralensis (licorice)/panax ginseng) root/amomum xanthioides seed/hordeum vulgare sprout/aralia cordata/achyranthes japonica extract safe during pregnancy?

Accepted Answer

The blend contains Glycyrrhiza (licorice) root extract, for which human and animal data (oral exposure) link maternal ingestion to adverse fetal/neuroendocrine outcomes; licorice constituents (glycyrrhizin/glycyrrhetinic acid) have demonstrated effects on corticosteroid metabolism and estrogenic activity, supporting a mechanism for reproductive/endocrine disruption. No EU Annex II/III ban or harmonised reproductive H-code for licorice extracts was found, so the hazard is scored as 'suspected' (h=2) rather than confirmed; topical cosmetic use gives low but measurable potential exposure (e=1) compared with oral intake. Sources: PubMed licorice pregnancy studies, CIR licorice safety review, ECHA substance pages, NCCIH summary, COSING listing.

Question 2

Is (astragalus membranaceus/glycyrrhiza uralensis (licorice)/panax ginseng) root/amomum xanthioides seed/hordeum vulgare sprout/aralia cordata/achyranthes japonica extract safe while breastfeeding?

Accepted Answer

There is limited direct evidence about transfer of licorice constituents into breastmilk after topical use; systemic effects are mainly documented with oral intake. Because licorice can alter steroid metabolism (demonstrated mechanism) there is a theoretical risk to the nursing infant but insufficient direct evidence to raise the hazard above h=1 for topical cosmetic exposure. Dermal absorption from typical cosmetics is likely low (e=1).

Question 3

Is (astragalus membranaceus/glycyrrhiza uralensis (licorice)/panax ginseng) root/amomum xanthioides seed/hordeum vulgare sprout/aralia cordata/achyranthes japonica extract safe for baby skin?

Accepted Answer

Infant skin has higher absorption (surface-area-to-weight and immature barrier), so exposure score is increased by +1; hazard and mechanism remain the same as for pregnancy (licorice-related endocrine activity/epidemiology), yielding h=2 and m=2. There are no infant-specific dermal toxicity studies for this full multi‑botanical extract to justify increasing hazard or mechanism beyond adult scores.

Question 4

How does VeriMom score (astragalus membranaceus/glycyrrhiza uralensis (licorice)/panax ginseng) root/amomum xanthioides seed/hordeum vulgare sprout/aralia cordata/achyranthes japonica extract?

Accepted Answer

VeriMom scores (astragalus membranaceus/glycyrrhiza uralensis (licorice)/panax ginseng) root/amomum xanthioides seed/hordeum vulgare sprout/aralia cordata/achyranthes japonica extract at 40/100 (medium risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.

Question 5

What are pregnancy-safe alternatives to (astragalus membranaceus/glycyrrhiza uralensis (licorice)/panax ginseng) root/amomum xanthioides seed/hordeum vulgare sprout/aralia cordata/achyranthes japonica extract?

Accepted Answer

See our curated list of pregnancy-safe alternatives to (astragalus membranaceus/glycyrrhiza uralensis (licorice)/panax ginseng) root/amomum xanthioides seed/hordeum vulgare sprout/aralia cordata/achyranthes japonica extract based on similar function and a no-known-risks safety band.

(astragalus membranaceus/glycyrrhiza uralensis (licorice)/panax ginseng) root/amomum xanthioides seed/hordeum vulgare sprout/aralia cordata/achyranthes japonica extract

Regulatory Data

Sources & references

Pregnancy-Safe Alternatives to (astragalus membranaceus/glycyrrhiza uralensis (licorice)/panax ginseng) root/amomum xanthioides seed/hordeum vulgare sprout/aralia cordata/achyranthes japonica extract | VeriMom

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