VeriMomarbutin est-il sûr pendant la grossesse ?
Regulatory reviews (CIR) and SCCS-derived material do not indicate a harmonised reproductive classification for arbutin; no evidence of human teratogenicity or harmonised H360/H361 classification was found (CIR, SCCS, ECHA/CosIng). A theoretical mechanistic concern exists because arbutin can be enzymatically hydrolysed to hydroquinone (PubChem, PubMed), but there is no robust animal or human reproductive toxicity data implicating arbutin itself, so hazard is scored as 0 and mechanism as theoretical (1). Dermal absorption from typical cosmetic use is low but measurable, so exposure is scored as 1 (CIR, CosIng, PubChem).
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Frequently asked questions
- arbutin est-il sûr pendant la grossesse ?
- Regulatory reviews (CIR) and SCCS-derived material do not indicate a harmonised reproductive classification for arbutin; no evidence of human teratogenicity or harmonised H360/H361 classification was found (CIR, SCCS, ECHA/CosIng). A theoretical mechanistic concern exists because arbutin can be enzymatically hydrolysed to hydroquinone (PubChem, PubMed), but there is no robust animal or human reproductive toxicity data implicating arbutin itself, so hazard is scored as 0 and mechanism as theoretical (1). Dermal absorption from typical cosmetic use is low but measurable, so exposure is scored as 1 (CIR, CosIng, PubChem).
- arbutin est-il sûr pendant l'allaitement ?
- No data indicate arbutin is a reproductive or lactation toxicant and there is no harmonised CLP reproductive classification (ECHA Annex VI/CosIng). Theoretical concern from possible conversion to hydroquinone applies (PubChem, PubMed), but no demonstrated transfer into milk or breastfeeding-specific adverse effects were identified. Dermal exposure is low but measurable in cosmetics, so exposure is scored 1.
- arbutin est-il sûr pour la peau de bébé ?
- No infant-specific reproductive or developmental toxicity evidence for arbutin was identified (CIR, SCCS, PubMed). Mechanistic concern (possible hydroquinone release) remains theoretical only. Because infant skin has higher permeability and surface-area-to-weight, measurable adult dermal absorption (see above) leads to an increased exposure score for babies (+1), so exposure is scored 2.
- Comment VeriMom évalue-t-il arbutin ?
- VeriMom évalue arbutin à 87/100 (risque faible) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à arbutin pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à arbutin basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.