Ist trichosanthes kirilowii root extract in der Schwangerschaft sicher?

Schwangerschaftssichere Alternativen zu trichosanthes kirilowii root extract | VeriMom

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Ist trichosanthes kirilowii root extract in der Schwangerschaft sicher?

Animal and mechanistic data show trichosanthin (from T. kirilowii root) is embryotoxic/abortifacient and has been used clinically to induce abortion, so reproductive hazard is supported (h=2). The mechanism is demonstrated (ribosome‑inactivating protein with demonstrated abortion mechanisms in experimental studies), so m=2. For topical cosmetic use exposure is likely low but measurable (e=1) because extracts are applied topically and some dermal uptake or local activity is possible depending on formulation; however systemic exposure from typical cosmetic topical use is likely limited. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/8102209/?utm_source=openai))

Ist trichosanthes kirilowii root extract während des Stillens sicher?

Because the same demonstrable reproductive/embryotoxic hazard exists for trichosanthin and systemic exposure (even small) could theoretically transfer into breastmilk, breastfeeding is flagged at the same hazard and mechanism level (h=2, m=2). Expected dermal/topical exposure is low but measurable (e=1); no direct data on lactational transfer from topical cosmetic use were found. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/8102209/?utm_source=openai))

Ist trichosanthes kirilowii root extract sicher für Babyhaut?

Hazard and mechanism are unchanged for infant skin (h=2, m=2) because the same toxic constituent (trichosanthin) is responsible. Exposure score is increased by +1 for baby skin to e=2 because infant skin has a higher surface‑area‑to‑weight ratio and less mature barrier, making dermal absorption and systemic exposure more likely from topical application of products containing the extract. No infant‑specific safety studies for topical T. kirilowii root extract were located. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/8102209/?utm_source=openai))

Wie bewertet VeriMom trichosanthes kirilowii root extract?

VeriMom bewertet trichosanthes kirilowii root extract mit 40/100 (mittleres Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.

Was sind schwangerschaftssichere Alternativen zu trichosanthes kirilowii root extract?

Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu trichosanthes kirilowii root extract basierend auf ähnlicher Funktion.