Ist polygonum cuspidatum root extract in der Schwangerschaft sicher?
Polygonum cuspidatum root extract is a botanical source of resveratrol (and related stilbenes). Resveratrol is a phytoestrogen with demonstrated estrogen receptor agonist/partial‑agonist activity in vitro and in vivo, giving a class/mechanistic concern (m=2) but there is no EU Annex II ban or confirmed harmonised CLP H360/H350/H340 for the extract — thus hazard is scored as 1. Topical/percutaneous absorption of resveratrol is low-to-measurable, so exposure is scored 1. (Sources: PubMed reviews/studies on resveratrol ER activity; in vitro/in vivo skin permeation studies; CosIng/CIR/Cosmetic lists show extract as a cosmetic ingredient, not banned.)
Schwangerschaftssichere Alternativen zu polygonum cuspidatum root extract | VeriMom
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Frequently asked questions
- Ist polygonum cuspidatum root extract in der Schwangerschaft sicher?
- Polygonum cuspidatum root extract is a botanical source of resveratrol (and related stilbenes). Resveratrol is a phytoestrogen with demonstrated estrogen receptor agonist/partial‑agonist activity in vitro and in vivo, giving a class/mechanistic concern (m=2) but there is no EU Annex II ban or confirmed harmonised CLP H360/H350/H340 for the extract — thus hazard is scored as 1. Topical/percutaneous absorption of resveratrol is low-to-measurable, so exposure is scored 1. (Sources: PubMed reviews/studies on resveratrol ER activity; in vitro/in vivo skin permeation studies; CosIng/CIR/Cosmetic lists show extract as a cosmetic ingredient, not banned.)
- Ist polygonum cuspidatum root extract während des Stillens sicher?
- Same rationale as pregnancy: phytoestrogenic activity of resveratrol provides a mechanistic concern but no harmonised CMR or EU cosmetic ban; topical exposure is low but measurable. Breastfeeding-specific transfer data for topical resveratrol/extract are lacking, so exposure is treated as low (e=1).
- Ist polygonum cuspidatum root extract sicher für Babyhaut?
- Hazard and mechanism same as adults (no infant‑specific evidence to change h or m). Because infants 0–3 yrs have an immature skin barrier and higher surface‑area‑to‑weight, exposure is increased by +1 (adult e=1 → infant e=2) when the ingredient/formulation allows measurable skin absorption (supported by dermal permeation studies for resveratrol).
- Wie bewertet VeriMom polygonum cuspidatum root extract?
- VeriMom bewertet polygonum cuspidatum root extract mit 60/100 (mittleres Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
- Was sind schwangerschaftssichere Alternativen zu polygonum cuspidatum root extract?
- Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu polygonum cuspidatum root extract basierend auf ähnlicher Funktion.
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Medizinischer Haftungsausschluss
Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.