VeriMomIst octoxynol-9 in der Schwangerschaft sicher?
CIR’s final/amended safety assessment concluded octoxynols (including octoxynol‑9) are safe as used in cosmetics and identified no harmonised reproductive hazard; a dedicated rat teratology study with intravaginal octoxynol‑9 reported no maternal or fetal developmental effects. However, in vitro and in vivo data show that octylphenol (the de‑ethoxylation product) is estrogenic — a mechanistic concern for the parent phenol exists but not demonstrated for octoxynol‑9 in pregnancy at cosmetic exposures. Skin absorption data in the safety assessment indicate low but measurable absorption from topical formulations, so exposure (e) is scored as 1 (low but measurable). Sources: CIR safety assessment; rat teratology study; review on 4‑tert‑octylphenol.
Pregnancy-safe products containing octoxynol-9
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Frequently asked questions
- Ist octoxynol-9 in der Schwangerschaft sicher?
- CIR’s final/amended safety assessment concluded octoxynols (including octoxynol‑9) are safe as used in cosmetics and identified no harmonised reproductive hazard; a dedicated rat teratology study with intravaginal octoxynol‑9 reported no maternal or fetal developmental effects. However, in vitro and in vivo data show that octylphenol (the de‑ethoxylation product) is estrogenic — a mechanistic concern for the parent phenol exists but not demonstrated for octoxynol‑9 in pregnancy at cosmetic exposures. Skin absorption data in the safety assessment indicate low but measurable absorption from topical formulations, so exposure (e) is scored as 1 (low but measurable). Sources: CIR safety assessment; rat teratology study; review on 4‑tert‑octylphenol.
- Ist octoxynol-9 während des Stillens sicher?
- No authoritative safety assessment (CIR) or harmonised classification flags reproductive/teratogenic effects for octoxynol‑9 and clinical/breastfeeding specific adverse outcomes are not reported in the high‑priority literature. Lactation databases and older clinical reports on related spermicides (nonoxynol‑9) did not show infant harm; nevertheless, low systemic absorption is possible and theoretical transfer in milk cannot be entirely excluded, so exposure is scored as 1 (low but measurable).
- Ist octoxynol-9 sicher für Babyhaut?
- CIR concluded octoxynols are safe as used but noted irritation concerns for some uses; skin absorption studies cited in the CIR/amended report indicate measurable absorption for octoxynols. Because infant skin (0–3 yr) has higher surface‑area‑to‑weight and an immature barrier, exposure is increased by +1 relative to adults (adult e=1 → baby e=2). There is no infant‑specific evidence demonstrating elevated hazard or a different mechanism in babies.
- Wie bewertet VeriMom octoxynol-9?
- VeriMom bewertet octoxynol-9 mit 93/100 (keine bekannten Risiken) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
- Was sind schwangerschaftssichere Alternativen zu octoxynol-9?
- Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu octoxynol-9 basierend auf ähnlicher Funktion.
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Medizinischer Haftungsausschluss
Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.