Ist glycyrrhiza uralensis root extract in der Schwangerschaft sicher?
No harmonised CLP reproductive classification (ECHA Annex VI) or SCCS/CIR conclusion that this extract is a reproductive teratogen; therefore hazard score remains 0 per rules. However, multiple peer-reviewed reports show constituent-specific endocrine activity in vitro (e.g., liquiritigenin is an ER agonist; glycyrrhizin/glycyrrhetinic acid have biological activity), so a demonstrated mechanistic effect is present (m=2). For topical use, systemic exposure is low but measurable depending on formulation, so exposure scored as 1. Sources: ECHA (no harmonised classification), PubMed (in vitro endocrine activity of licorice constituents), PubChem (constituent data), CosIng/EWG summaries.
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Frequently asked questions
- Ist glycyrrhiza uralensis root extract in der Schwangerschaft sicher?
- No harmonised CLP reproductive classification (ECHA Annex VI) or SCCS/CIR conclusion that this extract is a reproductive teratogen; therefore hazard score remains 0 per rules. However, multiple peer-reviewed reports show constituent-specific endocrine activity in vitro (e.g., liquiritigenin is an ER agonist; glycyrrhizin/glycyrrhetinic acid have biological activity), so a demonstrated mechanistic effect is present (m=2). For topical use, systemic exposure is low but measurable depending on formulation, so exposure scored as 1. Sources: ECHA (no harmonised classification), PubMed (in vitro endocrine activity of licorice constituents), PubChem (constituent data), CosIng/EWG summaries.
- Ist glycyrrhiza uralensis root extract während des Stillens sicher?
- No human/animal data establishing reproductive or developmental toxicity via dermal cosmetic use or lactation and no harmonised classification; hazard remains 0. Mechanistic in vitro endocrine activity of constituents supports m=2. Dermal absorption from cosmetics is low but measurable; breastmilk transfer after topical cosmetic use is unlikely but not well studied, so exposure scored 1. Sources: PubMed (constituent endocrine activity), ECHA (no CLP reprotox classification), PubChem, EWG.
- Ist glycyrrhiza uralensis root extract sicher für Babyhaut?
- No infant-specific evidence of reproductive/developmental toxicity from cosmetic topical use and no harmonised reprotoxic classification; hazard remains 0. Mechanistic evidence (in vitro estrogenic activity of constituents) justifies m=2. Exposure is increased for babies vs adults due to immature barrier and higher surface-area-to-weight; adult exposure scored 1 -> baby exposure increased to 2. Sources: PubMed (mechanistic studies on liquiritigenin/glycyrrhizin), CosIng/PubChem summaries, EWG.
- Wie bewertet VeriMom glycyrrhiza uralensis root extract?
- VeriMom bewertet glycyrrhiza uralensis root extract mit 80/100 (geringes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
- Was sind schwangerschaftssichere Alternativen zu glycyrrhiza uralensis root extract?
- Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu glycyrrhiza uralensis root extract basierend auf ähnlicher Funktion.
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Medizinischer Haftungsausschluss
Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.