Ist glycyrrhetinic acid in der Schwangerschaft sicher?

Schwangerschaftssichere Alternativen zu glycyrrhetinic acid | VeriMom

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Frequently asked questions

Ist glycyrrhetinic acid in der Schwangerschaft sicher?

Glycyrrhetinic acid is not listed in EU Annex II/III nor has a harmonised reproductive classification, but multiple human and mechanistic studies show it inhibits placental 11β‑HSD2 and maternal licorice (glycyrrhizin → glycyrrhetinic acid) intake is associated with adverse fetal/neurodevelopmental outcomes — supporting a 'suspected' reproductive hazard. ([echa.europa.eu](https://echa.europa.eu/substance-information/-/substanceinfo/100.006.769?utm_source=openai))

Ist glycyrrhetinic acid während des Stillens sicher?

No harmonised CLP reproductive/teratogenic classification was found; however the demonstrated mechanism (11β‑HSD2 inhibition) is relevant to glucocorticoid exposure. Systemic transfer to breastmilk after topical use is expected to be low but measurable if significant percutaneous absorption occurs. ([echa.europa.eu](https://echa.europa.eu/substance-information/-/substanceinfo/100.006.769?utm_source=openai))

Ist glycyrrhetinic acid sicher für Babyhaut?

There is no infant‑specific evidence of teratogenicity from topical use, but because glycyrrhetinic acid has demonstrated biological activity (11β‑HSD2 inhibition) and infant skin has higher absorption per kg, exposure score is increased for 0–3 yr. No EU ban/restriction was identified for topical cosmetic use. ([echa.europa.eu](https://echa.europa.eu/substance-information/-/substanceinfo/100.006.769?utm_source=openai))

Wie bewertet VeriMom glycyrrhetinic acid?

VeriMom bewertet glycyrrhetinic acid mit 40/100 (mittleres Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.

Was sind schwangerschaftssichere Alternativen zu glycyrrhetinic acid?

Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu glycyrrhetinic acid basierend auf ähnlicher Funktion.