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Ist capryloyl salicylic acid in der Schwangerschaft sicher?

Animal developmental data show effects at high doses (dermal application in pregnant rats: increased incomplete ossification at 100 mg/kg/day; NOAEL for developmental toxicity 40 mg/kg/day), so reproductive/developmental hazard is suspected based on animal evidence; there is no harmonised CLP reproductive classification and CIR concluded cosmetic use at reported concentrations is safe. Dermal absorption in vitro is low but measurable (~6% penetrated deeper than the stratum corneum in a 16 h Franz cell study), so exposure from typical topical cosmetic use is low but measurable.

Inhaltsstoffe
capryloyl salicylic acid
MITTLERES RISIKO
53
/100
0

Schwangerschaftssichere Alternativen zu capryloyl salicylic acid | VeriMom

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Ist capryloyl salicylic acid in der Schwangerschaft sicher?
Animal developmental data show effects at high doses (dermal application in pregnant rats: increased incomplete ossification at 100 mg/kg/day; NOAEL for developmental toxicity 40 mg/kg/day), so reproductive/developmental hazard is suspected based on animal evidence; there is no harmonised CLP reproductive classification and CIR concluded cosmetic use at reported concentrations is safe. Dermal absorption in vitro is low but measurable (~6% penetrated deeper than the stratum corneum in a 16 h Franz cell study), so exposure from typical topical cosmetic use is low but measurable.
Ist capryloyl salicylic acid während des Stillens sicher?
No direct data on excretion in milk were identified; because animal developmental effects exist (see pregnancy section) the ingredient is treated as a suspected reproductive/developmental hazard. Maternal topical exposure gives low but measurable dermal penetration (CIR data), so systemic exposure cannot be excluded though milk transfer data are absent.
Ist capryloyl salicylic acid sicher für Babyhaut?
Do not increase hazard without infant-specific evidence; however exposure score is increased by +1 for infants because CIR reports measurable dermal penetration in adults (~6% beyond stratum corneum and ~17% in stratum corneum by tape‑strip), and infant skin has higher absorption per weight. There are no infant-specific safety studies; CIR considered cosmetic uses (max reported leave‑on 0.5%) acceptable given available data.
Wie bewertet VeriMom capryloyl salicylic acid?
VeriMom bewertet capryloyl salicylic acid mit 53/100 (mittleres Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
Was sind schwangerschaftssichere Alternativen zu capryloyl salicylic acid?
Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu capryloyl salicylic acid basierend auf ähnlicher Funktion.

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Medizinischer Haftungsausschluss

Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.

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