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Ist ammonium glycyrrhizate in der Schwangerschaft sicher?

CIR’s final safety assessment includes ammonium glycyrrhizate and judges cosmetic use acceptable with typical use conditions, but independent human/epidemiological and toxicology assessments link glycyrrhizic/glycyrrhetinic acids (parent compounds) with pregnancy outcomes after oral exposure via inhibition of placental 11β‑HSD2 and associated fetal effects; therefore reproductive concern is suspected (h=2) with a demonstrated mechanism (m=2). For topical cosmetic use systemic absorption is expected to be low but measurable, so exposure score is 1. (Sources: CIR final report; VKM risk assessment; PBPK and human studies summarized in LactMed and literature).

Inhaltsstoffe
ammonium glycyrrhizate
MITTLERES RISIKO
40
/100
0

Schwangerschaftssichere Alternativen zu ammonium glycyrrhizate | VeriMom

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Frequently asked questions

Ist ammonium glycyrrhizate in der Schwangerschaft sicher?
CIR’s final safety assessment includes ammonium glycyrrhizate and judges cosmetic use acceptable with typical use conditions, but independent human/epidemiological and toxicology assessments link glycyrrhizic/glycyrrhetinic acids (parent compounds) with pregnancy outcomes after oral exposure via inhibition of placental 11β‑HSD2 and associated fetal effects; therefore reproductive concern is suspected (h=2) with a demonstrated mechanism (m=2). For topical cosmetic use systemic absorption is expected to be low but measurable, so exposure score is 1. (Sources: CIR final report; VKM risk assessment; PBPK and human studies summarized in LactMed and literature).
Ist ammonium glycyrrhizate während des Stillens sicher?
Glycyrrhizic acid (parent) has been detected in breastmilk after maternal oral intake and systemic effects are reported with ingestion; mechanism (11β‑HSD2 inhibition and systemic glycyrrhetinic metabolites) is demonstrated. For topical cosmetic use transfer to milk from topical use is unlikely but possible at low measurable levels, so exposure =1 and hazard =2 pending significant systemic exposure. (Sources: LactMed/NCBI; CIR; VKM).
Ist ammonium glycyrrhizate sicher für Babyhaut?
No infant‑specific topical hazard data found; hazard and mechanism remain linked to the parent glycyrrhizic/glycyrrhetinic acids (h=2, m=2). Because infant skin has higher per‑kg absorption, raise exposure by +1 compared with adults (adult e=1 → infant e=2) when the ingredient shows measurable absorption. No evidence supports increasing hazard or mechanism scores for infants in the absence of infant‑specific toxicology. (Sources: CIR; VKM; LactMed).
Wie bewertet VeriMom ammonium glycyrrhizate?
VeriMom bewertet ammonium glycyrrhizate mit 40/100 (mittleres Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
Was sind schwangerschaftssichere Alternativen zu ammonium glycyrrhizate?
Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu ammonium glycyrrhizate basierend auf ähnlicher Funktion.

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Medizinischer Haftungsausschluss

Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.

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