Sollte ich sassafras officinale bark extract in der Schwangerschaft meiden? | VeriMom
Sassafras bark/root extracts can contain the alkenylbenzene safrole, which is harmonised/classified in the EU as a carcinogen (CLP Category 1B/H350/H351) and is prohibited in cosmetics; carcinogenic/mutagenic hazards are treated as high reproductive concern. Safrole’s metabolic activation leads to DNA adduct formation (demonstrated mechanism). Exposure from topical cosmetic use is low–but measurable unless the extract is guaranteed safrole-free. (ECHA substance data; NTP/Report on Carcinogens; PubMed reviews of alkenylbenzenes).
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FAQ
- Ist sassafras officinale bark extract in der Schwangerschaft sicher?
- Sassafras bark/root extracts can contain the alkenylbenzene safrole, which is harmonised/classified in the EU as a carcinogen (CLP Category 1B/H350/H351) and is prohibited in cosmetics; carcinogenic/mutagenic hazards are treated as high reproductive concern. Safrole’s metabolic activation leads to DNA adduct formation (demonstrated mechanism). Exposure from topical cosmetic use is low–but measurable unless the extract is guaranteed safrole-free. (ECHA substance data; NTP/Report on Carcinogens; PubMed reviews of alkenylbenzenes).
- Ist sassafras officinale bark extract während des Stillens sicher?
- Same basis as pregnancy: presence of safrole (harmonised EU classification as a CMR) makes the ingredient high hazard for lactation context. Topical exposures are low–but measurable; transfer into milk is not well characterised for cosmetic topical use, but CMR classification and genotoxic mechanism justify a high hazard rating. (ECHA; NTP; SCF/PubMed reviews).
- Ist sassafras officinale bark extract sicher für Babyhaut?
- Hazard and mechanism mirror adult/pregnancy because safrole is a harmonised CMR 1B. Exposure score is increased for infants (+1) because infant skin has higher surface-area-to-weight and less mature barrier, so a measurable topical exposure becomes a moderate exposure for 0–3 yr. Where the extract is confirmed safrole-free, these scores would change. (ECHA; NTP; PubMed reviews).
- Wie bewertet VeriMom sassafras officinale bark extract?
- VeriMom bewertet sassafras officinale bark extract mit 20/100 (hohes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
- Was sind schwangerschaftssichere Alternativen zu sassafras officinale bark extract?
- Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu sassafras officinale bark extract basierend auf ähnlicher Funktion.
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Medizinischer Haftungsausschluss
Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.