Sollte ich salicylamide in der Schwangerschaft meiden? | VeriMom
ECHA REACH/registration data include Repr.2 / H361 notifications for salicylamide (CAS 65-45-2) submitted by registrants (not a harmonised Annex VI classification). This supports a 'suspected' reproductive hazard (h=2) but is not harmonised by the Commission. Mechanistic concern is class-based/theoretical (m=1) because salicylamide is a salicylate-related compound and salicylates are known to cross the placenta and be systemically available; direct mechanistic reproductive data for salicylamide are limited. Exposure from typical topical cosmetic use is expected to be low but measurable (evidence for dermal cosmetic exposure is limited), so e=1.
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Ist salicylamide in der Schwangerschaft sicher?
- ECHA REACH/registration data include Repr.2 / H361 notifications for salicylamide (CAS 65-45-2) submitted by registrants (not a harmonised Annex VI classification). This supports a 'suspected' reproductive hazard (h=2) but is not harmonised by the Commission. Mechanistic concern is class-based/theoretical (m=1) because salicylamide is a salicylate-related compound and salicylates are known to cross the placenta and be systemically available; direct mechanistic reproductive data for salicylamide are limited. Exposure from typical topical cosmetic use is expected to be low but measurable (evidence for dermal cosmetic exposure is limited), so e=1.
- Ist salicylamide während des Stillens sicher?
- Registrants have notified H361 (Repr.2) for salicylamide; salicylate metabolites are known to be excreted in human milk (class-based evidence), so a suspected hazard to nursing infants is appropriate (h=2) but this is based on registrant classification and read-across from salicylates rather than a harmonised/regulatory SCCS/CIR conclusion for salicylamide specifically. Systemic exposure after topical use is likely low but non-zero (e=1).
- Ist salicylamide sicher für Babyhaut?
- Hazard (h) and mechanism (m) are kept the same as adult because there is no infant-specific evidence to upscore hazard or mechanism. Exposure (e) is increased by +1 for infants (e=2) per your rules because infant skin has higher surface‑area‑to‑weight and an immature barrier and salicylamide is a small molecule with some dermal absorption potential; therefore infant dermal exposure is moderately greater than adult.
- Wie bewertet VeriMom salicylamide?
- VeriMom bewertet salicylamide mit 27/100 (hohes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
- Was sind schwangerschaftssichere Alternativen zu salicylamide?
- Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu salicylamide basierend auf ähnlicher Funktion.
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Medizinischer Haftungsausschluss
Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.