VeriMomSollte ich retinyl retinoate in der Schwangerschaft meiden? | VeriMom
No harmonised ECHA H360 classification or specific reproductive/teratology studies were located for retinyl retinoate itself, so a confirmed H360-level hazard cannot be assigned; however it is a retinoid ester that can produce retinoid activity and retinoic-acid-mediated developmental effects are well‑characterised, so a class-based theoretical reproductive concern is justified (h=1). The mechanism is well‑characterised as retinoic acid receptor agonism and metabolic conversion to active retinoid species in skin (m=3). Topical absorption is low but measurable for retinyl esters per SCCS (exposure order: retinyl esters << retinol < retinal < retinoic acid), so adult topical exposure is scored low but measurable (e=1).
ECHA regulatory hazard statements
- •H360
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FAQ
- Ist retinyl retinoate in der Schwangerschaft sicher?
- No harmonised ECHA H360 classification or specific reproductive/teratology studies were located for retinyl retinoate itself, so a confirmed H360-level hazard cannot be assigned; however it is a retinoid ester that can produce retinoid activity and retinoic-acid-mediated developmental effects are well‑characterised, so a class-based theoretical reproductive concern is justified (h=1). The mechanism is well‑characterised as retinoic acid receptor agonism and metabolic conversion to active retinoid species in skin (m=3). Topical absorption is low but measurable for retinyl esters per SCCS (exposure order: retinyl esters << retinol < retinal < retinoic acid), so adult topical exposure is scored low but measurable (e=1).
- Ist retinyl retinoate während des Stillens sicher?
- No direct data on transfer of retinyl retinoate into human milk were found. By analogy to other topical retinoid esters and because retinoids have a known receptor‑mediated mechanism, a theoretical class-based concern for nursing infants applies (h=1) and the mechanism remains retinoid receptor activity (m=3). Systemic exposure from typical topical cosmetic use is expected to be low but measurable, so exposure via maternal use during breastfeeding is scored low (e=1).
- Ist retinyl retinoate sicher für Babyhaut?
- No infant-specific toxicology studies for retinyl retinoate were found. Hazard remains a class-based theoretical retinoid concern (h=1) with the same retinoid receptor mechanism (m=3). Because infant skin (0–3 yr) has higher surface-area-to-weight and an immature barrier, exposure score is increased by +1 from adult topical use (adult e=1 → baby e=2) when measurable dermal absorption exists. Note: SCCS has evaluated retinol and common retinyl esters and recommends concentration limits/warnings; retinoic acid itself is banned in cosmetics (SCCS).
- Wie bewertet VeriMom retinyl retinoate?
- VeriMom bewertet retinyl retinoate mit 13/100 (hohes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
- Was sind schwangerschaftssichere Alternativen zu retinyl retinoate?
- Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu retinyl retinoate basierend auf ähnlicher Funktion.
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Medizinischer Haftungsausschluss
Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.